BDBM74208 2,4-bis(oxidanyl)benzoic acid::2,4-dihydroxybenzoic acid::MLS001055408::SMR001227190::beta-Resorcylic acid::cid_1491

SMILES c1cc(c(cc1O)O)C(=O)O

InChI Key InChIKey=UIAFKZKHHVMJGS-UHFFFAOYSA-N

Data  7 KI  1 IC50  1 EC50

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 74208   

TargetProtein LANA1(HHV-8)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM74208(beta-Resorcylic acid | MLS001055408 | SMR001227190...)
Affinity DataEC50: >7.50E+4nMAssay Description:Primary Collaborators: Kenneth Kaye,Brigham & Womens,Boston MA,kkaye@rics.bwh.harvard.edu,617-525-4256 Chantal Beauchemin,Brigham & Womens,Boston MA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay
TargetAlpha-(1,3)-fucosyltransferase 7(Human)
Schering-Plough Research Institute

LigandPNGBDBM74208(beta-Resorcylic acid | MLS001055408 | SMR001227190...)
Affinity DataIC50: 2.00E+5nMpH: 7.3 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM74208(beta-Resorcylic acid | MLS001055408 | SMR001227190...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM74208(beta-Resorcylic acid | MLS001055408 | SMR001227190...)
Affinity DataKi:  5.20E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM74208(beta-Resorcylic acid | MLS001055408 | SMR001227190...)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM74208(beta-Resorcylic acid | MLS001055408 | SMR001227190...)
Affinity DataKi:  6.80E+4nMAssay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM74208(beta-Resorcylic acid | MLS001055408 | SMR001227190...)
Affinity DataKi:  7.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM74208(beta-Resorcylic acid | MLS001055408 | SMR001227190...)
Affinity DataKi:  7.20E+4nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM74208(beta-Resorcylic acid | MLS001055408 | SMR001227190...)
Affinity DataKi:  5.30E+5nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2013
Entry Details
PubMed