BDBM16431 2-(naphthalen-2-yl)acetic acid::2-Napthylacetic acid::Betoxan::CHEMBL948::beta-Naphthylacetic acid::naphthalen-2-ylacetic acid

SMILES c1ccc2cc(ccc2c1)CC(=O)O

InChI Key InChIKey=VIBOGIYPPWLDTI-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16431   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Brown University

Curated by ChEMBL
LigandPNGBDBM16431(Betoxan | CHEMBL948 | beta-Naphthylacetic acid | n...)
Affinity DataIC50: 3.50E+6nMAssay Description:Inhibitory activity against Yersinia Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Medical College of Wiscosin

LigandPNGBDBM16431(Betoxan | CHEMBL948 | beta-Naphthylacetic acid | n...)
Affinity DataKi:  6.20E+3nM ΔG°:  -7.10kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2007
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1 [W220Y,C299A](Human)
Medical College of Wiscosin

LigandPNGBDBM16431(Betoxan | CHEMBL948 | beta-Naphthylacetic acid | n...)
Affinity DataKi:  9.40E+4nMAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2007
Entry Details Article
PubMed