BDBM50080274 Benzyl-phosphonic acid::CHEMBL299737::Phenyl-methanephosphonic acid anion::benzylphosphonic acid

SMILES c1ccc(cc1)CP(=O)(O)O

InChI Key InChIKey=OGBVRMYSNSKIEF-UHFFFAOYSA-N

Data  5 KI  1 IC50  1 Kd

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50080274   

TargetTyrosine-protein kinase Lck(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50080274(Phenyl-methanephosphonic acid anion | Benzyl-phosp...)
Affinity DataKd:  5.90E+6nMAssay Description:Binding affinity against Lck SH2 domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstatic acid phosphatase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50080274(Phenyl-methanephosphonic acid anion | Benzyl-phosp...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human prostatic acid phosphatase was determined as inhibition of the hydrolysis of tyrosine phosphateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetAlkaline phosphatase, germ cell type(Human)
Utah State University

Curated by ChEMBL
LigandPNGBDBM50080274(Phenyl-methanephosphonic acid anion | Benzyl-phosp...)
Affinity DataKi:  5.80E+5nMAssay Description:Inhibition of Human Placental alkaline Phosphatase (PLAP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Campinas

Curated by ChEMBL
LigandPNGBDBM50080274(Phenyl-methanephosphonic acid anion | Benzyl-phosp...)
Affinity DataKi:  3.00E+6nMAssay Description:Inhibition of PTP1B (unknown origin) using nPP substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Bovine)
University of Campinas

Curated by ChEMBL
LigandPNGBDBM50080274(Phenyl-methanephosphonic acid anion | Benzyl-phosp...)
Affinity DataKi:  1.40E+6nMAssay Description:Inhibition of bovine intestinal 5'-nucleotide phosphodiesterase using 4-nitrophenyl phenylphosphonate substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetAlkaline phosphatase, placental type(Human)
University of Campinas

Curated by ChEMBL
LigandPNGBDBM50080274(Phenyl-methanephosphonic acid anion | Benzyl-phosp...)
Affinity DataKi:  5.80E+5nMAssay Description:Inhibition of human placental alkaline phosphatase using p-nitrophenyl phosphate substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetMandelate racemase(Pseudomonas putida (g-Proteobacteria))
Dalhousie University

Curated by ChEMBL
LigandPNGBDBM50080274(Phenyl-methanephosphonic acid anion | Benzyl-phosp...)
Affinity DataKi:  3.60E+6nMpH: 7.5Assay Description:Inhibition constant against Mandelate racemase from Pseudomonas putida at pH 7.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed