BDBM772 Benzamidine::CHEMBL79897::[amino(phenyl)methylidene]azanium::benzamidine deriv.::benzamidinium chloride
SMILES c1ccc(cc1)C(=[NH2+])N
InChI Key InChIKey=PXXJHWLDUBFPOL-UHFFFAOYSA-O
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 772
Affinity DataIC50: 4.40E+5nMpH: 8.0 T: 2°CAssay Description:The cleavage of the substrate was followed by monitoring the change in fluorescence at 460 nm (excitation at 365 nm) for 25 min at room temperature o...More data for this Ligand-Target Pair
Affinity DataKi: 4.80E+3nM ΔG°: -7.18kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nM ΔG°: -6.34kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+4nM ΔG°: -6.31kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Affinity DataKi: 2.90E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Affinity DataKi: 3.90E+4nM ΔG°: -6.01kcal/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
Affinity DataKi: 9.50E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Affinity DataKi: 9.70E+4nM ΔG°: -5.42kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Affinity DataKi: 3.20E+5nM ΔG°: -4.72kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+5nM ΔG°: -5.34kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Affinity DataKi: 7.50E+5nM ΔG°: -4.22kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Affinity DataKi: 1.65E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+5nM ΔG°: -5.11kcal/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nM ΔG°: >-4.09kcal/molepH: 8.0 T: 2°CAssay Description:The measurements were carried out on a microplate reader. Two concentrations of the substrate and five concentrations of the inhibitor were used in t...More data for this Ligand-Target Pair
Affinity DataKi: 3.80E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
Affinity DataKi: 6.03E+5nM ΔG°: -4.40kcal/molepH: 8.05 T: 2°CAssay Description:All readings were made in a Hitachi-Coleman ultraviolet-visible 101 spectrophotometer.More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 4 hits for monomerid = 772
ITC DataΔG°: -6.42kcal/mole −TΔS°: -2.37kcal/mole ΔH°: -4.06kcal/mole logk: 6.20E+4
pH: 8.0 T: 20.10°C
pH: 8.0 T: 20.10°C
ITC DataΔG°: -6.35kcal/mole −TΔS°: -1.84kcal/mole ΔH°: -4.51kcal/mole logk: 4.50E+4
pH: 8.0 T: 25.10°C
pH: 8.0 T: 25.10°C
ITC DataΔG°: -6.38kcal/mole −TΔS°: -1.29kcal/mole ΔH°: -5.11kcal/mole logk: 4.10E+4
pH: 8.0 T: 30.00°C
pH: 8.0 T: 30.00°C
ITC DataΔG°: -6.38kcal/mole −TΔS°: -0.719kcal/mole ΔH°: -5.66kcal/mole logk: 3.10E+4
pH: 8.0 T: 37.10°C
pH: 8.0 T: 37.10°C