BDBM50010101 2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate::Bentyl::Bicyclohexyl-1-carboxylic acid 2-diethylamino-ethyl ester::CHEMBL1123::DICYCLOMINE::Dicycloverin

SMILES CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1

InChI Key InChIKey=CURUTKGFNZGFSE-UHFFFAOYSA-N

Data  9 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50010101   

LigandPNGBDBM50010101(Dicycloverin | CHEMBL1123 | Bentyl | 2-(diethylami...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50010101(Dicycloverin | CHEMBL1123 | Bentyl | 2-(diethylami...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
Glaxo Group Research

Curated by PDSP Ki Database
LigandPNGBDBM50010101(Dicycloverin | CHEMBL1123 | Bentyl | 2-(diethylami...)
Affinity DataKi:  0.620nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2011
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor(Rabbit)
Glaxo Group Research

Curated by PDSP Ki Database
LigandPNGBDBM50010101(Dicycloverin | CHEMBL1123 | Bentyl | 2-(diethylami...)
Affinity DataKi:  1.51nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2011
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M3(Rat)
Glaxo Group Research

Curated by PDSP Ki Database
LigandPNGBDBM50010101(Dicycloverin | CHEMBL1123 | Bentyl | 2-(diethylami...)
Affinity DataKi:  1.78nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2011
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
Glaxo Group Research

Curated by PDSP Ki Database
LigandPNGBDBM50010101(Dicycloverin | CHEMBL1123 | Bentyl | 2-(diethylami...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]pirenzepine from muscarinic acetylcholine receptor M1 in rat cortex homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
National Institute of Mental Health

Curated by PDSP Ki Database
LigandPNGBDBM50010101(Dicycloverin | CHEMBL1123 | Bentyl | 2-(diethylami...)
Affinity DataKi:  5.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M4(Chicken)
Glaxo Group Research

Curated by PDSP Ki Database
LigandPNGBDBM50010101(Dicycloverin | CHEMBL1123 | Bentyl | 2-(diethylami...)
Affinity DataKi:  5.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2011
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
National Institute of Mental Health

Curated by PDSP Ki Database
LigandPNGBDBM50010101(Dicycloverin | CHEMBL1123 | Bentyl | 2-(diethylami...)
Affinity DataKi:  32.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2011
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
National Institute of Mental Health

Curated by PDSP Ki Database
LigandPNGBDBM50010101(Dicycloverin | CHEMBL1123 | Bentyl | 2-(diethylami...)
Affinity DataKi:  47nMAssay Description:Displacement of [3H](-)-quinuclidinyl benzilate(QNB) from muscarinic (M2) receptor in rat heart homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
National Institute of Mental Health

Curated by PDSP Ki Database
LigandPNGBDBM50010101(Dicycloverin | CHEMBL1123 | Bentyl | 2-(diethylami...)
Affinity DataKi:  244nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details
PubMed