BDBM50021952 7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid::Amfonelic acid::CHEMBL35337

SMILES CCn1cc(C(O)=O)c(=O)c2ccc(Cc3ccccc3)nc12

InChI Key InChIKey=WHHHJDGNBVQNAU-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50021952   

TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50021952(CHEMBL35337 | 7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-[...)
Affinity DataKi:  3.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMed
LigandPNGBDBM50021952(CHEMBL35337 | 7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-[...)
Affinity DataKi:  7.20nMAssay Description:Inhibition of the uptake of tritiated dopamine (DA) in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50021952(CHEMBL35337 | 7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-[...)
Affinity DataKi:  9.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMed
LigandPNGBDBM50021952(CHEMBL35337 | 7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-[...)
Affinity DataKi:  18.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021952(CHEMBL35337 | 7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-[...)
Affinity DataKi:  41nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50021952(CHEMBL35337 | 7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-[...)
Affinity DataKi:  74.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50021952(CHEMBL35337 | 7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-[...)
Affinity DataKi:  210nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMed
LigandPNGBDBM50021952(CHEMBL35337 | 7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-[...)
Affinity DataKi:  879nMAssay Description:Inhibition the uptake of tritiated serotonin (5-HT) by the serotonin transporter SERT in rat synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetNorepinephrine transporter(Rat)
Harvard University

Curated by PDSP Ki Database
LigandPNGBDBM50021952(CHEMBL35337 | 7-Benzyl-1-ethyl-4-oxo-1,4-dihydro-[...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2012
Entry Details Article
PubMed