BDBM50249188 Alphitolic acid::CHEMBL511805

SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)C(O)=O

InChI Key InChIKey=PFCVZKFJHRCLCC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50249188   

TargetZinc finger protein GLI1(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50249188(Alphitolic acid | CHEMBL511805)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of Gli1-mediated transcription expressed in human PANC1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetZinc finger protein GLI1(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50249188(Alphitolic acid | CHEMBL511805)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of GLI1-mediated transcriptional activity in human HaCaT cells by luciferase based reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50249188(Alphitolic acid | CHEMBL511805)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of biotinylated consensus sequence binding to NF-kB p65 in human HeLa nuclear extracts after 3 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed