BDBM50192334 CHEMBL426141::adociasulfate-2

SMILES C[C@]12CC[C@H]3[C@@](C)(CC[C@@H]4[C@]3(C)CC[C@@H]3O[C@@]5(C)CCCC(C)(C)[C@@H]5CC[C@@]43C)[C@@H]1Cc1c2c(OS([O-])(=O)=O)ccc1OS([O-])(=O)=O

InChI Key InChIKey=XXJQNRPPCJSVDF-UHFFFAOYSA-L

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50192334   

TargetKinesin-like protein KIF11(Human)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50192334(adociasulfate-2 | CHEMBL426141)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of kinesin ATPase activity by enzyme-linked inorganic phosphate detection assay without preincubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50192334(adociasulfate-2 | CHEMBL426141)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of kinesin ATPase activity by enzyme-linked inorganic phosphate detection assay with 5 mins pre-incubationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50192334(adociasulfate-2 | CHEMBL426141)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Eg5 assessed as inhibition of microtubule-induced ATPase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
University of Georgia

Curated by ChEMBL
LigandPNGBDBM50192334(adociasulfate-2 | CHEMBL426141)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Eg5 basal ATPase activity (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed