BDBM50395519 ADIPHENINE

SMILES CCN(CC)CCOC(=O)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=JGOAIQNSOGZNBX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50395519   

TargetHistamine H1 receptor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395519(ADIPHENINE)
Affinity DataIC50: 1.12E+5nMAssay Description:Antagonist activity at H1 receptor in human HeLa cells assessed as inhibition of histamine-induced Ca2+ release by using fura-2AM-based fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395519(ADIPHENINE)
Affinity DataIC50: 1.70E+4nMAssay Description:Displacement of [3H]mepyramine from histamine H1 receptor in Sprague-Dawley rat brain membrane after 2 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395519(ADIPHENINE)
Affinity DataIC50: 1.58E+5nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed