BDBM50306696 8-Benzyloxycaffeine::CHEMBL602259::cid_223566

SMILES Cn1c(OCc2ccccc2)nc2n(C)c(=O)n(C)c(=O)c12

InChI Key InChIKey=LSJWXGMOPMJCHP-UHFFFAOYSA-N

Data  5 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50306696   

LigandPNGBDBM50306696(CHEMBL602259 | cid_223566 | 8-Benzyloxycaffeine)
Affinity DataEC50:  3.78E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2011
Entry Details
PCBioAssay
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50306696(CHEMBL602259 | cid_223566 | 8-Benzyloxycaffeine)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human recombinant MAOA assessed as 4-hydroxyquinoline formation by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50306696(CHEMBL602259 | cid_223566 | 8-Benzyloxycaffeine)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of human recombinant MAOB assessed as 4-hydroxyquinoline formation by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50306696(CHEMBL602259 | cid_223566 | 8-Benzyloxycaffeine)
Affinity DataKi:  430nMAssay Description:Inhibition of human recombinant MAOB assessed as 4-hydroxyquinoline formation by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50306696(CHEMBL602259 | cid_223566 | 8-Benzyloxycaffeine)
Affinity DataKi:  590nMAssay Description:Inhibition of human recombinant MAOA assessed as 4-hydroxyquinoline formation by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
North-West University

Curated by ChEMBL
LigandPNGBDBM50306696(CHEMBL602259 | cid_223566 | 8-Benzyloxycaffeine)
Affinity DataKi:  1.52E+3nMAssay Description:Displacement of [3H]DPCPX from adenosine receptor A1 in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2020
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
North-West University

Curated by ChEMBL
LigandPNGBDBM50306696(CHEMBL602259 | cid_223566 | 8-Benzyloxycaffeine)
Affinity DataKi:  1.93E+3nMAssay Description:Displacement of [3H]DPCPX from adenosine receptor A1 in rat brain membrane in presence of GTP by GTP shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Rat)
North-West University

Curated by ChEMBL
LigandPNGBDBM50306696(CHEMBL602259 | cid_223566 | 8-Benzyloxycaffeine)
Affinity DataKi:  4.30E+3nMAssay Description:Displacement of [3H]CGS21680 from adenosine receptor A2a in rat brain striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2020
Entry Details Article
PubMed