BDBM50240777 4alpha-phorbol-didecanoate::CHEMBL118987::Decanoic acid (1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-9-decanoyloxy-4a,7b-dihydroxy-3-hydroxymethyl-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-cyclopropa[3,4]benzo[1,2-e]azulen-9a-yl ester

SMILES CCCCCCCCCC(=O)O[C@@H]1[C@H]([C@]2([C@@H](C=C(C[C@@]3([C@H]2C=C(C3=O)C)O)CO)[C@H]4C1(C4(C)C)OC(=O)CCCCCCCCC)O)C

InChI Key InChIKey=DGOSGFYDFDYMCW-UHFFFAOYSA-N

Data  2 EC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240777   

LigandPNGBDBM50240777(Decanoic acid (1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-9-de...)
Affinity DataEC50:  370nMAssay Description:Activation of mouse wild type TRPV4 expressed in HEK293 cells assessed as increase in intracellular calcium concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50240777(Decanoic acid (1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-9-de...)
Affinity DataEC50:  370nMAssay Description:Agonist activity at mouse TRPV4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)