BDBM10960 (3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-[4-(propan-2-yl)phenyl]carbamate::4-isopropylphenserine::Cymserine::cymserine.tartaric acid

SMILES [H][C@]12N(C)CC[C@@]1(C)c1cc(OC(=O)Nc3ccc(cc3)C(C)C)ccc1N2C

InChI Key InChIKey=NKJRRVBTMYRXRB-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 10960   

TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10960(4-isopropylphenserine | (3aS,8aR)-1,3a,8-trimethyl...)
Affinity DataIC50: 760nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10960(4-isopropylphenserine | (3aS,8aR)-1,3a,8-trimethyl...)
Affinity DataIC50: 50nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10960(4-isopropylphenserine | (3aS,8aR)-1,3a,8-trimethyl...)
Affinity DataIC50: 760nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10960(4-isopropylphenserine | (3aS,8aR)-1,3a,8-trimethyl...)
Affinity DataIC50: 50nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetCholinesterase(Mouse)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM10960(4-isopropylphenserine | (3aS,8aR)-1,3a,8-trimethyl...)
Affinity DataIC50: 240nMAssay Description:Inhibition of mouse serum BChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10960(4-isopropylphenserine | (3aS,8aR)-1,3a,8-trimethyl...)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human BChE by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10960(4-isopropylphenserine | (3aS,8aR)-1,3a,8-trimethyl...)
Affinity DataIC50: 750nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM10960(4-isopropylphenserine | (3aS,8aR)-1,3a,8-trimethyl...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of mouse brain AChE after 1 hr by modified Ellman's colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10960(4-isopropylphenserine | (3aS,8aR)-1,3a,8-trimethyl...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10960(4-isopropylphenserine | (3aS,8aR)-1,3a,8-trimethyl...)
Affinity DataIC50: 50nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10960(4-isopropylphenserine | (3aS,8aR)-1,3a,8-trimethyl...)
Affinity DataIC50: 50nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10960(4-isopropylphenserine | (3aS,8aR)-1,3a,8-trimethyl...)
Affinity DataIC50: 758nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCholinesterase(Human)
National Institutes of Health

LigandPNGBDBM10960(4-isopropylphenserine | (3aS,8aR)-1,3a,8-trimethyl...)
Affinity DataIC50: 50nMAssay Description:Inhibition of BChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed