BDBM50320734 4-Hydroxy-benzoic acid hydrazide::4-hydroxybenzohydrazide::CHEMBL124267

SMILES c1cc(ccc1C(=O)NN)O

InChI Key InChIKey=ZMZGIVVRBMFZSG-UHFFFAOYSA-N

Data  2 KI  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50320734   

TargetLysine-specific demethylase 5A(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50320734(4-hydroxybenzohydrazide | 4-Hydroxy-benzoic acid h...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of KDM5A (unknown origin) using substrate peptide/ascorbate/2-OG/ Fe(2) as substrate preincubated for 15 mins followed by addition of subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetMyeloperoxidase(Human)
University Sarajevo School of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50320734(4-hydroxybenzohydrazide | 4-Hydroxy-benzoic acid h...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of MPO in human neutrophils using H2O2 as substrate measured after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCathepsin B(Goat)
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50320734(4-hydroxybenzohydrazide | 4-Hydroxy-benzoic acid h...)
Affinity DataKi:  1.90E+3nMAssay Description:Competitive inhibition of cathepsin B in goat liver using alpha-N-benzoyl-D,L-arginine-2-naphthylamide as substrate by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50320734(4-hydroxybenzohydrazide | 4-Hydroxy-benzoic acid h...)
Affinity DataKi:  1.77E+5nMAssay Description:Inhibition of mashroom tyrosinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed