BDBM50055282 2-Methyl-isothiourea::CHEMBL356703

SMILES CSC(N)=N

InChI Key InChIKey=SDDKIZNHOCEXTF-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50055282   

TargetNitric oxide synthase, inducible(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50055282(2-Methyl-isothiourea | CHEMBL356703)
Affinity DataIC50: 3.00E+3nMAssay Description:The compound was evaluated for the inhibitory potencies using human Inducible nitric oxide synthase (hiNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50055282(2-Methyl-isothiourea | CHEMBL356703)
Affinity DataIC50: 7.00E+3nMAssay Description:The compound was evaluated for the inhibitory potencies using human Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50055282(2-Methyl-isothiourea | CHEMBL356703)
Affinity DataKi:  160nMAssay Description:Inhibition of nNOS assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed