BDBM50316608 1H-Imidazol-2-yl-ammonium::1H-Imidazol-2-ylamine::1H-imidazol-2-amine::2-Aminoimidazole::CHEMBL2392115::CHEMBL291627

SMILES c1cnc([nH]1)N

InChI Key InChIKey=DEPDDPLQZYCHOH-UHFFFAOYSA-N

Data  1 KI  4 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50316608   

TargetNitric oxide synthase, brain(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50316608(1H-imidazol-2-amine | 2-Aminoimidazole | 1H-Imidaz...)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition rat recombinant nNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50316608(1H-imidazol-2-amine | 2-Aminoimidazole | 1H-Imidaz...)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of mouse recombinant iNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAmine oxidase [copper-containing] 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50316608(1H-imidazol-2-amine | 2-Aminoimidazole | 1H-Imidaz...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMembrane primary amine oxidase(Rat)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50316608(1H-imidazol-2-amine | 2-Aminoimidazole | 1H-Imidaz...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of rat VAP-1 expressed in CHO cells using [14C]-benzylamine as substrate preincubated for 30 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetArginase-1(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50316608(1H-imidazol-2-amine | 2-Aminoimidazole | 1H-Imidaz...)
Affinity DataKi:  3.60E+6nMAssay Description:Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed