BDBM50316030 1-aminopentylphosphonic acid::CHEMBL1089899::Nle-P (3)

SMILES CCCC[C@H](N)P(=O)(O)O

InChI Key InChIKey=NXTPDFMZKSLVRK-UHFFFAOYSA-N

Data  1 KI  1 IC50

PDB links: 5 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316030   

TargetAminopeptidase N(Pig)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50316030(1-aminopentylphosphonic acid | CHEMBL1089899 | Nle...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCytosol aminopeptidase [33-68,L62W](Pig)
Academy of Sciences of The Czech Republic

LigandPNGBDBM50316030(1-aminopentylphosphonic acid | CHEMBL1089899 | Nle...)
Affinity DataKi:  5.80E+4nM ΔG°:  -5.78kcal/molepH: 8.4 T: 2°CAssay Description:LAP was assayed in 75 mM triethanolamine hydrochloride buffer (pH = 8.4, containing 5 mM MgCl2) at 25°C. The substrate (L-leucine-p-nitroanilide) was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed