Compile Data Set for Download or QSAR
Report error Found 42 for UniProtKB: P62837
TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718803(US20250042896, Compound 123)
Affinity DataIC50: 5.40nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718795(Preparation of (S)-8-cyclopropyl-3-(5-(3-methyl-1-...)
Affinity DataIC50: 7.40nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718800(US20250042896, Compound 120-P2)
Affinity DataIC50: 7.80nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718782(Preparation of (S)-8-methyl-3-(3-(3-methyl-1-(4-me...)
Affinity DataIC50: 9.70nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718801(US20250042896, Compound 121)
Affinity DataIC50: 10.1nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718805(US20250042896, Compound 126)
Affinity DataIC50: 11.1nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718802(US20250042896, Compound 122)
Affinity DataIC50: 12.3nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718806(US20250042896, Compound 127)
Affinity DataIC50: 13.3nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718791(Preparation of 3-(3-((1R,3S)-3-fluoro-1-(4-methyl-...)
Affinity DataIC50: 15nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718787(Preparation of (S)-8-methyl-3-(5-(3-methyl-1-(4-me...)
Affinity DataIC50: 17nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718798(US20250042896, Compound 120)
Affinity DataIC50: 17.5nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718808(US20250042896, Compound 129)
Affinity DataIC50: 17.8nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718790(Preparation of (1S,3R)-3-(4-methyl-4H-1,2,4-triazo...)
Affinity DataIC50: 17.8nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718794(Preparation of (S)-8-cyclopropyl-3-(3-(3-methyl-1-...)
Affinity DataIC50: 19.1nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718804(Preparation of 3-(3-(cyclopropyl(4-methyl-4H-1,2,4...)
Affinity DataIC50: 19.7nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718784(US20250042896, Compound 62)
Affinity DataIC50: 23.6nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718769(US20250042896, Compound 2-P1)
Affinity DataIC50: 27.1nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718807(US20250042896, Compound 128)
Affinity DataIC50: 28.6nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718780(US20250042896, Compound 14)
Affinity DataIC50: 29.3nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718770(US20250042896, Compound 2-P2)
Affinity DataIC50: 30.5nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718777(US20250042896, Compound 11)
Affinity DataIC50: 31.2nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718779(US20250042896, Compound 13)
Affinity DataIC50: 31.9nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718796(US20250042896, Compound 88)
Affinity DataIC50: 32.7nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718786(Preparation of 3-(3-(cyclopropyl(4-methyl-4H-1,2,4...)
Affinity DataIC50: 38.4nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718768(Preparation of 3-[3-[3-methyl-1-(4-methyl-4H-1,2,4...)
Affinity DataIC50: 40.3nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718785(Preparation of 3-(3-(cyclopropyl(4-methyl-4H-1,2,4...)
Affinity DataIC50: 41.6nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718797(US20250042896, Compound 89)
Affinity DataIC50: 41.6nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718776(US20250042896, Compound 10)
Affinity DataIC50: 42.9nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718783(Preparation of (S)-6-(3-(3-methyl-1-(4-methyl-4H-1...)
Affinity DataIC50: 43.1nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718778(US20250042896, Compound 12)
Affinity DataIC50: 63.9nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718793(Preparation of (S)-3-(3-(3,3-difluoro-1-(4-methyl-...)
Affinity DataIC50: 64.9nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718701(Preparation of 3-[3-[3-methyl-1-(4-methyl-4H-1,2,4...)
Affinity DataIC50: 76.6nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718788(Preparation of (S)-8-methyl-3-(3-(3-methyl-1-(4-me...)
Affinity DataIC50: 88.9nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718789(Preparation of (S)-8-methyl-3-(3-(2-(4-methyl-4H-1...)
Affinity DataIC50: 96.4nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718775(US20250042896, Compound 9)
Affinity DataIC50: 130nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718781(US20250042896, Compound 17)
Affinity DataIC50: 168nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718792(Preparation of 8-methyl-3-(3-(2-(4-methyl-4H-1,2,4...)
Affinity DataIC50: 203nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718799(US20250042896, Compound 120-P1)
Affinity DataIC50: 212nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718772(US20250042896, Compound 4)
Affinity DataIC50: 268nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718771(US20250042896, Compound 3)
Affinity DataIC50: 296nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718774(US20250042896, Compound 8)
Affinity DataIC50: 366nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase CBL-B/(E3-independent) E2 ubiquitin-conjugating enzyme D2(Human)
Hainan Simcere Zaiming Pharmaceutical Co.

US Patent
LigandPNGBDBM718773(US20250042896, Compound 5)
Affinity DataIC50: 450nMAssay Description:Experiment purpose: Testing of inhibitory activity of compounds on the interaction between Cbl-b protein and UbcH5B-Ub. Experimental method: Eu-Ubqui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/12/2025
Entry Details
Go to US Patent