13 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Development and structural analysis of adenosine site binding tankyrase inhibitors.
University of Oulu
Discovery of potent and selective nonplanar tankyrase inhibiting nicotinamide mimics.
University of Oulu
Chemical probes to study ADP-ribosylation: synthesis and biochemical evaluation of inhibitors of the human ADP-ribosyltransferase ARTD3/PARP3.
Ume£
Discovery of novel, induced-pocket binding oxazolidinones as potent, selective, and orally bioavailable tankyrase inhibitors.
Amgen
Fragment-based ligand design of novel potent inhibitors of tankyrases.
Nanyang Technological University
Discovery of 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827): a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.
Irbm/Merck Research Laboratories
Discovery and SAR of novel, potent and selective hexahydrobenzonaphthyridinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1).
Irbm-Merck Research Laboratories Rome
Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3.
Institutet
Bivalent diazo bicyclic Smac mimetics and the uses thereof
The Regents of The University of Michigan
Design, synthesis, and biological evaluation of new 3-hydroxy-2-oxo-3-trifluoromethylindole as potential HIV-1 reverse transcriptase inhibitors
Instituto De Tecnologia Em Fa��Rmacos
Discovery of PDK1 kinase inhibitors with a novel mechanism of action by ultrahigh throughput screening.
Merck Research Laboratories