The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

24 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.EBI
University of Oxford
Dual-target kinase drug design: Current strategies and future directions in cancer therapy.EBI
Sichuan University
Discovery of a series of 8-(1-phenylpyrrolidin-2-yl)-6-carboxamide-2-morpholino-4H-chromen-4-one as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours.EBI
Astrazeneca
Bicyclic urea kinase inhibitors and uses thereofBDB
The General Hospital
Compositions and methods for treating KIT- and PDGFRA-mediated diseasesBDB
Blueprint Medicines
Substituted (4'-hydroxyphenyl)cyclohexane compounds and uses thereof as selective agonists of the estrogen receptor beta isoformBDB
Marquette University
Bipyrazole derivatives as JAK inhibitorsBDB
Incyte
Quinazoline derivative and preparation method thereforBDB
Chia Tai Tianqing Pharmaceutical Group
Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitorsBDB
Acetylon Pharmaceuticals
Beta-alanine derivatives, pharmaceutically acceptable salts thereof, and pharmaceutical composition comprising same as active ingredientBDB
Korea Research Institute of Chemical Technology
Acid addition salt of substituted pyridine compoundBDB
Daiichi Sankyo
Synthetic Triterpenoid Inhibition of Human Ghrelin O-Acyltransferase: The Involvement of a Functionally Required Cysteine Provides Mechanistic Insight into Ghrelin Acylation.BDB
Syracuse University
Chemotype-selective modes of action of ¿-opioid receptor agonists.BDB
University of North Carolina
Potent poxvirus inhibitorBDB
University of Pennsylvania
Substituted amide compoundsBDB
Pfizer
Tricyclic indole derivatives useful endothelial lipase inhibitorsBDB
Janssen Pharmaceutica
Nitrogen-containing compounds and pharmaceutical compositions thereof for the treatment of atrial fibrillationBDB
Otsuka Pharmaceutical
Treatment of respiratory disorders using TRPA1 antagonistsBDB
Glenmark Pharmaceuticals
Design, synthesis and antitumor activity of novel pyrazolo[3,4-d]pyrimidine derivatives as EGFR-TK inhibitors.BDB
Beni-Suef University
ß-Hydroxyacyl-acyl Carrier Protein Dehydratase (FabZ) from Francisella tularensis and Yersinia pestis: Structure Determination, Enzymatic Characterization, and Cross-Inhibition Studies.BDB
Brookhaven National Laboratory
Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein.BDB
Monash University
Benzodioxole piperidine compoundsBDB
Hoffmann-La Roche
Tyrosinase inhibition: conformational analysis based studies on molecular dynamics calculations of bipiperidine based inhibitors.BDB
University of Karachi