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22 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Identification of indole inhibitors of human hematopoietic prostaglandin D2 synthase (hH-PGDS).EBI
Astrazeneca
Novel benzoxazole inhibitors of mPGES-1.EBI
Pfizer
Investigation of the binding pocket of human hematopoietic prostaglandin (PG) D2 synthase (hH-PGDS): a tale of two waters.EBI
Pfizer
Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D(2) synthases.EBI
The University of Queensland
Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D2 synthase.EBI
The University of Queensland
The exploration of aza-quinolines as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors with low brain exposure.EBI
Glaxosmithkline
Structure-activity relationship study of PROTACs against hematopoietic prostaglandin DEBI
National Institute of Health Sciences
Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design.EBI
National Institute of Health Sciences
A knowledge-based, structural-aided discovery of a novel class of 2-phenylimidazo[1,2-a]pyridine-6-carboxamide H-PGDS inhibitors.EBI
Glaxosmithkline
Novel amide and imidazole compounds as potent hematopoietic prostaglandin DEBI
Cayman Chemical
Development of a Hematopoietic Prostaglandin D Synthase-Degradation Inducer.EBI
National Institute of Health Sciences
The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors.EBI
Glaxosmithkline
Characterization of crystal water molecules in a high-affinity inhibitor and hematopoietic prostaglandin D synthase complex by interaction energy studies.EBI
Riken Center For Biosystems Dynamics Research
Amelioration of mechanism-based inactivation of CYP3A4 by a H-PGDS inhibitor.EBI
Sanofi Us
Inhibitors of cyclin-dependent kinase 7 (CDK7)BDB
Syros Pharmaceuticals
Pyrazolo[1,5-A]PYRAZIN-4-YL derivativesBDB
Pfizer
Serine protease inhibitorsBDB
The Medicines Company (Leipzig)
BAY36-7620: a potent non-competitive mGlu1 receptor antagonist with inverse agonist activity.BDB
Upr 9023
Design of mutation-resistant HIV protease inhibitors with the substrate envelope hypothesis.BDB
University of Maryland
Discovery and initial SAR of arylsulfonylpiperazine inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1).BDB
Amgen