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BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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44 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 4. 3-[2-(Benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one and analogues.EBI
Merck Reserch Laboratories
Synergistic combination of immunologic inhibitors for the treatment of cancerBDB
The University of Chicago
Indole carboxamide derivatives as P2X7 receptor antagonistsBDB
Actelion Pharmaceuticals
Therapeutic hydroxyquinolonesBDB
Rutgers, The State University of New Jersey
Azabenzimidazole derivativesBDB
Boehringer Ingelheim International
Dihydrooxazine or oxazepine derivatives having BACE1 inhibitory activityBDB
Shionogi
7-hydroxy-indolinyl antagonists of P2Y1 receptorBDB
Bristol-Myers Squibb
Pyrrole six-membered heteroaryl ring derivative, preparation method thereof, and medicinal uses thereofBDB
Jiangsu Hengrui Medicine
Substituted 1,7-naphthyridines as dopamine D1 ligandsBDB
Pfizer
Fused thiazin-3-ones as KCA3.1 inhibitorsBDB
Boehringer Ingelheim International
Substituted N-heteroaryl spirolactam bipyrrolidines, preparation and therapeutic use thereofBDB
Sanofi
Modified biotin, mutant streptavidin, and use thereofBDB
Savid Therapeutics
Fused tricyclic amide compounds as multiple kinase inhibitorsBDB
Beigene
Heteroaryl compounds and methods of use thereofBDB
Sunovion Pharmaceuticals
5-HT3 receptor antagonistsBDB
Takeda Pharmaceutical
Toll-like receptor 2-agonistic lipopeptides, and method of making the sameBDB
University of Kansas
Pyrimido-diazepinone compounds and methods of treating disordersBDB
Dana-Farber Cancer Institute
Pharmacologically active compoundsBDB
The University of Liverpool
Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compoundsBDB
Array Biopharma
Substituted pyrazolo[1,5-a]pyrazines as negative allosteric modulators of metabotropic glutamate receptor 3BDB
Vanderbilt University
Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infectionBDB
Hoffmann-La Roche
Muscarinic agonistsBDB
Acadia Pharmaceuticals
Serine/threonine kinase inhibitorsBDB
Array Biopharma
Compounds and pharmaceutical compositions thereof for the treatment of inflammatory disordersBDB
Galapagos
Fused tricyclic urea compounds as Raf kinase and/or Raf kinase dimer inhibitorsBDB
Beigene
Substituted triazolopyridinesBDB
Bayer Pharma Aktiengesellschaft
Methyl- and trifluoromethyl-substituted pyrrolopyridine modulators of RORC2 and methods of use thereofBDB
Pfizer
Thiazole-substituted aminoheteroaryls as Spleen Tyrosine Kinase inhibitorsBDB
Merck Sharp & Dohme
Trifluoromethyl-oxadiazole derivatives and their use in the treatment of diseaseBDB
Novartis
Pyridyl-and pyrimidinyl-substituted pyrrole-, thiophene- and furane-derivatives as kinase inhibitorsBDB
Nerviano Medical Sciences
Substituted 6,7-dialkoxy-3-isoquinolinol derivatives as inhibitors of phosphodiesterase 10 (PDE 10A)BDB
Allergan
Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activityBDB
Boehringer Ingelheim International
Cyclosporin analogues for preventing or treating hepatitis C infectionBDB
Enanta Pharmaceuticals
4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine groupBDB
Bayer Intellectual Property
Substituted biaryl compoundBDB
Ube Industries
Cyclopropylamine derivatives useful as LSD1 inhibitorsBDB
Oryzon Genomics
Arylaminoalcohol-substituted 2,3-dihydroimidazo[1,2-C]quinolinesBDB
Bayer Intellectual Property
Substituted tetrazolo[1,5-a]pyrazines as ROR-gamma inhibitorsBDB
Merck Patent
Substituted condensed pyrimidine compoundsBDB
GrÜNenthal
Macrocyclic urea and sulfamide derivatives as inhibitors of TAFIaBDB
Sanofi
Novel modifications in the alkenyldiarylmethane (ADAM) series of non-nucleoside reverse transcriptase inhibitors.BDB
Purdue University
Compulsory order of substrate binding to herpes simplex virus type 1 thymidine kinase. A calorimetric study.BDB
Swiss Federal Institute of Technology
Thermodynamics of substrate binding to the chaperone SecB.BDB
Indian Institute of Science
Energetic roles of hydrogen bonds at the ureido oxygen binding pocket in the streptavidin-biotin complex.BDB
University of Washington