24 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Discovery of XEN445: a potent and selective endothelial lipase inhibitor raises plasma HDL-cholesterol concentration in mice.
Xenon Pharmaceuticals
Endothelial lipase inhibitors for the treatment of atherosclerosis and cardiovascular disorders.
Therachem Research Medilab (India)
A thiocarbamate inhibitor of endothelial lipase raises HDL cholesterol levels in mice.
Janssen Research and Development
Design and synthesis of boronic acid inhibitors of endothelial lipase.
Tufts University School of Medicine
Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors.
Glaxosmithkline
Benzothiazole-based compounds as potent endothelial lipase inhibitors.
Bristol-Myers Squibb
Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase.
Bristol-Myers Squibb
Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors.
Bristol-Myers Squibb
Identification of Reversible Small Molecule Inhibitors of Endothelial Lipase (EL) That Demonstrate HDL-C Increase In Vivo.
TBA
Benzopyrroloxazines containing a bridgehead nitrogen atom as promising scaffolds for the achievement of biologically active agents.
University of Calabria
PK/PD Disconnect Observed with a Reversible Endothelial Lipase Inhibitor.
Bristol-Myers Squibb
Structure-activity relationship studies of benzyl-, phenethyl-, and pyridyl-substituted tetrahydroacridin-9-amines as multitargeting agents to treat Alzheimer's disease.
University of Waterloo
Structure and function of PA4872 from Pseudomonas aeruginosa, a novel class of oxaloacetate decarboxylase from the PEP mutase/isocitrate lyase superfamily.
University of Maryland Biotechnology Institute
Human cytochrome P450 2E1 structures with fatty acid analogs reveal a previously unobserved binding mode.
The University of Kansas
Comparison of [Dmt1]DALDA and DAMGO in binding and G protein activation at mu, delta, and kappa opioid receptors.
Cornell University
A human somatostatin receptor (SSTR3), located on chromosome 22, displays preferential affinity for somatostatin-14 like peptides.
University of Toronto
Cloning and pharmacologic characterization of a thromboxane A2 receptor from K562 (human chronic myelogenous leukemia) cells.
University of Cincinnati
Actions of phenylglycine analogs at subtypes of the metabotropic glutamate receptor family.
Novo Nordisk
Characterization of alpha-2 adrenergic receptors in the OK cell, an opossum kidney cell line.
University of Missouri