42 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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Discovery and analgesic evaluation of 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione as a novel potent d-amino acid oxidase inhibitor.
Shanghai Jiao Tong University
D-Amino acid oxidase inhibitors based on the 5-hydroxy-1,2,4-triazin-6(1H)-one scaffold.
Johns Hopkins University
Identification of Novel D-Aspartate Oxidase Inhibitors by in Silico Screening and Their Functional and Structural Characterization in Vitro.
Kitasato University
6-Hydroxy-1,2,4-triazine-3,5(2H,4H)-dione Derivatives as Novel D-Amino Acid Oxidase Inhibitors.
Johns Hopkins University
Synthesis and biological activity of 5-(4-methoxyphenyl)-oxazole derivatives.
Kitasato University
Structure-Metabolism Relationships in the Glucuronidation of d-Amino Acid Oxidase Inhibitors.
Johns Hopkins University
Synthesis of kojic acid derivatives as secondary binding site probes of D-amino acid oxidase.
Johns Hopkins University
Structural, kinetic, and pharmacodynamic mechanisms of D-amino acid oxidase inhibition by small molecules.
Sunovion Pharmaceuticals
Synthesis and SAR study of new thiazole derivatives as vascular adhesion protein-1 (VAP-1) inhibitors for the treatment of diabetic macular edema: part 2.
Astellas Pharma
4-Hydroxypyridazin-3(2H)-one derivatives as novel D-amino acid oxidase inhibitors.
Astellas Pharma
Identification of novel D-amino acid oxidase inhibitors by in silico screening and their functional characterization in vitro.
Kitasato University
Synthesis and SAR study of new thiazole derivatives as vascular adhesion protein-1 (VAP-1) inhibitors for the treatment of diabetic macular edema.
Astellas Pharma
Synthesis and SAR of 1-hydroxy-1H-benzo[d]imidazol-2(3H)-ones as Inhibitors of D-Amino Acid Oxidase.
TBA
The discovery and development of selective 3-fluoro-4-aryloxyallylamine inhibitors of the amine oxidase activity of semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1).
Pharmaxis
Biophysical and physicochemical methods differentiate highly ligand-efficient human D-amino acid oxidase inhibitors.
Abbott Healthcare Products
The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors.
Merck Sharp & Dohme
Discovery of a Novel Class of d-Amino Acid Oxidase Inhibitors Using the Schrödinger Computational Platform.
Schr£Dinger
The inhibition of monoamine oxidase by 2H-1,4-benzothiazin-3(4H)-ones.
North-West University
Combining monoamine oxidase B and semicarbazide-sensitive amine oxidase enzyme inhibition to address inflammatory disease.
Pharmaxis
2-Aminomethylene-5-sulfonylthiazole Inhibitors of Lysyl Oxidase (LOX) and LOXL2 Show Significant Efficacy in Delaying Tumor Growth.
University of Manchester
Identification and Optimization of Mechanism-Based Fluoroallylamine Inhibitors of Lysyl Oxidase-like 2/3.
Pharmaxis
Structural basis for potent inhibition of d-amino acid oxidase by thiophene carboxylic acids.
Tokushima University
Discovery of d-amino acid oxidase inhibitors based on virtual screening against the lid-open enzyme conformation.
Hungarian Academy of Sciences
Discovery of isatin and 1H-indazol-3-ol derivatives as d-amino acid oxidase (DAAO) inhibitors.
Hungarian Academy of Sciences
Compound having PD-L1 inhibitory activity, preparation method therefor and use thereof
Shanghai Ennovabio Pharmaceuticals
Certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamides as dipeptidyl peptidase 1 inhibitors
Astrazeneca
Aryl- and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline
Vitae Pharmaceuticals
HSPC-sparing treatments for RB-positive abnormal cellular proliferation
Gi Therapeutics
Synthesis and binding study of certain 6-arylalkanamides as molecular probes for cannabinoid receptor subtypes.
Cairo University
Fragment Profiling Approach to Inhibitors of the Orphan M. tuberculosis P450 CYP144A1.
University of Cambridge
1,4-dihydro-naphthyridine derivative and pharmaceutical composition and use thereof
Jiangsu Simovay Pharmaceutical
Substituted piperidinyl-pyridazinyl derivatives useful as SCD 1 inhibitors
Janssen Pharmaceutica
Pyrimidine compounds as inhibitors of protein kinases IKK epsilon and/or TBK-1, processes for their preparation, and pharmaceutical compositions containing them
Domainex
Synthesis and biological evaluation of new donepezil-like Thiaindanones as AChE inhibitors.
Centre D'Etudes Et De Recherche Sur Le MÉDicament De Normandie
Selective aurora kinase inhibitors identified using a taxol-induced checkpoint sensitivity screen.
Harvard Medical School