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BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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18 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis of quaternarya-amino acid-based arginase inhibitors via the Ugi reaction.EBI
Institutes For Pharmaceutical Discovery
2-Substituted-2-amino-6-boronohexanoic acids as arginase inhibitors.EBI
Institutes For Pharmaceutical Discovery
Discovery of (R)-2-amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic acid and congeners as highly potent inhibitors of human arginases I and II for treatment of myocardial reperfusion injury.EBI
Institutes For Pharmaceutical Discovery
Binding ofa,a-disubstituted amino acids to arginase suggests new avenues for inhibitor design.EBI
Drexel University
Chemical similarities and differences among inhibitors of nitric oxide synthase, arginase and dimethylarginine dimethylaminohydrolase-1: Implications for the design of novel enzyme inhibitors modulating the nitric oxide pathway.EBI
Flinders University
Recent advances in small molecule based cancer immunotherapy.EBI
Southern Medical University
If small molecules immunotherapy comes, can the prime be far behind?EBI
Zhejiang University
Targeting Metalloenzymes by Boron-Containing Metal-Binding Pharmacophores.EBI
Sichuan University
Amino-cyclohexane Carboxylic Acid Inhibitors of Arginase.EBI
Arrival Discovery
Boronic acid-based arginase inhibitors in cancer immunotherapy.EBI
Oncoarendi Therapeutics
Novel Arginase Inhibitors for Treating Cancer and Respiratory Inflammatory Diseases.EBI
Smith, Gambrell & Russell
Rational design of novel irreversible inhibitors for human arginase.EBI
Brown University
CDK8/19 inhibitorsBDB
Joint Stock Company “Biocad”
Compounds and uses thereofBDB
Foghorn Therapeutics
Purine derivatives and the use thereof as medicamentBDB
Boehringer Ingelheim International
Somatostatin modulators and uses thereofBDB
Crinetics Pharmaceuticals
Iminothiazoline-Sulfonamide Hybrids as Jack Bean Urease Inhibitors; Synthesis, Kinetic Mechanism and Computational Molecular Modeling.BDB
Quaid-I-Azam University