BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

8 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of potent and selective CDK8 inhibitors from an HSP90 pharmacophore.EBI
Merck
Discovery of potent and selective CDK8 inhibitors through FBDD approach.EBI
Roche Innovation Center Shanghai
Discovery of 1-(4-(4-Amino-3-(4-(2-morpholinoethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea (CHMFL-FLT3-213) as a Highly Potent Type II FLT3 Kinase Inhibitor Capable of Overcoming a Variety of FLT3 Kinase Mutants in FLT3-ITD Positive AML.EBI
Chinese Academy of Sciences
Substituted pyrimido[5,4-d]pyrimidines as HER2 inhibitorsBDB
Array Biopharma
PCSK9 inhibitors and methods of use thereofBDB
Astrazeneca
Triazolopyrimidine compounds and uses thereofBDB
Novartis
Piperidine derivatives as inhibitors of ubiquitin specific protease 7BDB
Almac Discovery
Regulators of aldehyde dehydrogenase ALDH3A1 and related therapeutic methodsBDB
Indiana University Research and Technology