BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.5M data for 737K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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9 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Identification and SAR of selective inducible nitric oxide synthase (iNOS) dimerization inhibitors.EBI
Kalypsys
Discovery of dual inducible/neuronal nitric oxide synthase (iNOS/nNOS) inhibitor development candidate 4-((2-cyclobutyl-1H-imidazo[4,5-b]pyrazin-1-yl)methyl)-7,8-difluoroquinolin-2(1H)-one (KD7332) part 2: identification of a novel, potent, and selective series of benzimidazole-quinolinone iNOS/nNOEBI
Kalypsys
Synthesis and SAR of 2-aryl-3-aminomethylquinolines as agonists of the bile acid receptor TGR5.EBI
Kalypsys
Benzothiophene containing Rho kinase inhibitors: Efficacy in an animal model of glaucoma.EBI
Kalypsys
Water-soluble PDE4 inhibitors for the treatment of dry eye.EBI
Kalypsys
Identification of KD5170: a novel mercaptoketone-based histone deacetylase inhibitor.EBI
Kalypsys
Alpha-mercaptoketone based histone deacetylase inhibitors.EBI
Kalypsys
Multitarget FAAH and COX inhibitors and therapeutical uses thereofBDB
Fondazione Istituto Italiano Di Tecnologia
Potent human immunodeficiency virus type 1 protease inhibitors that utilize noncoded D-amino acids as P2/P3 ligands.BDB
Eli Lilly