14 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Acyclic phosph(on)ate inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase.
Industrial Research
Transition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimics.
Industrial Research
Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase.
Industrial Research
Second generation transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase.
Industrial Research
Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase.
Industrial Research
Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase.
Industrial Research
Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase.
Industrial Research
A fluorescent probe for GM1 gangliosidosis relatedß-galactosidase: N-(dansylamino)hexylaminocarbonylpentyl-1,5-dideoxy-1,5-imino-D-galactitol.
Industrial Research
Synthesis and Toll-like receptor 4 (TLR4) activity of phosphatidylinositol dimannoside analogues.
Industrial Research
Design and synthesis of potent"sulfur-free" transition state analogue inhibitors of 5'-methylthioadenosine nucleosidase and 5'-methylthioadenosine phosphorylase.
Industrial Research
8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases.
Industrial Research
Substituted 1,4-benzodiazepine-2,5-diones as alpha-helix mimetic antagonists of the HDM2-p53 protein-protein interaction.
Johnson & Johnson Pharmaceutical Research & Development