26 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).
Forma Therapeutics
Discovery of potent and efficacious cyanoguanidine-containing nicotinamide phosphoribosyltransferase (Nampt) inhibitors.
Forma Therapeutics
Structure-based discovery of novel amide-containing nicotinamide phosphoribosyltransferase (nampt) inhibitors.
Forma Therapeutics
Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (Nampt) inhibitors.
Forma Therapeutics
Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN).
Forma Therapeutics
Discovery and Optimization of Quinolinone Derivatives as Potent, Selective, and Orally Bioavailable Mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors.
Forma Therapeutics
Structure-Based Design and Identification of FT-2102 (Olutasidenib), a Potent Mutant-Selective IDH1 Inhibitor.
Forma Therapeutics
Design and Optimization of Benzopiperazines as Potent Inhibitors of BET Bromodomains.
Forma Therapeutics
Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11.
Forma Therapeutics
2-AMINOPYRIMIDINE COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF AND APPLICATION THEREOF
Guangzhou Salustier Biosciences
Substituted dihydrothienopyrimidines and their use as phosphodiesterase inhibitors
Union Therapeutics
Compound as selective JAK inhibitor, and salt and therapeutic use thereof
Suzhou Longbiotech Pharmaceuticals
Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors
Fedora Pharmaceuticals
Fused heterocyclic ring compounds and method of treating retinal disease using same
The Industry & Academic Cooperation In Chungnam National University (IAC)
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors.
University of Lubeck
The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis.
Fred Hutchinson Cancer Research Center