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BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.5M data for 737K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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17 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of ABT-957: 1-Benzyl-5-oxopyrrolidine-2-carboxamides as selective calpain inhibitors with enhanced metabolic stability.EBI
Abbvie Deutschland
Novel, potent, selective, and brain penetrant phosphodiesterase 10A inhibitors.EBI
Abbvie Deutschland
Novel, potent, selective and brain penetrant vasopressin 1b receptor antagonists.EBI
Abbvie Deutschland
Mitigating the Metabolic Liability of Carbonyl Reduction: Novel Calpain Inhibitors with P1' Extension.EBI
Abbvie Deutschland
Discovery of Novel Aminotetralines and Aminochromanes as Selective and Competitive Glycine Transporter 1 (GlyT1) Inhibitors.EBI
Abbvie Deutschland
Discovery of Novel and Highly Selective Inhibitors of Calpain for the Treatment of Alzheimer's Disease: 2-(3-Phenyl-1H-pyrazol-1-yl)-nicotinamides.EBI
Abbvie Deutschland
Aminostatin derivatives for the treatment of arthrosisBDB
Merck Patent
Substituted tetrahydrocarbazole and carbazole carboxamide compoundsBDB
Bristol-Myers Squibb
A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N-Methyltransferase.BDB
Utrecht University
Benzoxazole- and tetrahydrobenzoxazole-substituted pyridazinones as GPR119 agonistsBDB
Boehringer Ingelheim International
Pyrimidine derivatives, preparation thereof, and pharmaceutical use thereof as akt(pkb) phosphorylation inhibitorsBDB
Sanofi
Pyrimidine-4,6-diamine derivatives as PI3K inhibitorsBDB
Incyte Holdings
The structural basis for the interaction between L-tryptophan and the Escherichia coli trp aporepressor.BDB
University of Chicago
Characterization of I2 imidazoline and sigma binding sites in the rat and human stomach.BDB
University of Bonn
Triptolide directly inhibits dCTP pyrophosphatase.BDB
Yale University
Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor.BDB
Northwestern University