26 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy.

Mitobridge, Inc. (An Astellas)
Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity.

Rapt Therapeutics
The medicinal chemistry of mitochondrial dysfunction: a critical overview of efforts to modulate mitochondrial health.

Msd The Francis Crick Institute
N-(5-SUBSTITUTED-[(1,3,4-THIADIAZOLYL) OR (THIAZOLYL)])(SUBSTITUTED)CARBOXAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING HUMAN POLYMERASE THETA

Repare Therapeutics
MALT1 MODULATORS AND USES THEREOF

Rheos Medicines
2-AMINOPYRIMIDINE COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF AND APPLICATION THEREOF

Guangzhou Salustier Biosciences
CRYSTALLINE FORM OF TLR8 AGONIST

Chia Tai Tianqing Pharmaceutical Group
COMPOUND USEFUL AS CDK7 KINASE INHIBITOR AND USE THEREOF

Tyk Medicines
Treatment of upper aerodigestive tract disorders and cough

Individual
Serine/threonine kinase inhibitors

Genentech
Compounds

Tmem16A
Benzamide compounds

Recurium Ip Holding
Ghrelin O-acyltransferase inhibitors

Glaxosmithkline Intellectual Property Development
Pyrazolo-heteroaryl derivative, preparation method and medical use thereof

Jiangsu Hengrui Medicine
Substituted imidazo[1,2-c]pyrimidines as PRC2 inhibitors

Mirati Therapeutics
Oxopicolinamide derivative, preparation method therefor and pharmaceutical use thereof

Jiangsu Hengrui Medicine
Quinolinone lysyl oxidase-like 2 inhibitors and uses thereof

Pharmakea
Aromatic acetylene or aromatic ethylene compound, intermediate, preparation method, pharmaceutical composition and use thereof

TBA
Ethynyl derivatives

Hoffmann-La Roche
Alkyl pyrrolopyrimidine analogs and methods of making and using same

The University of North Carolina At Chapel Hill
Small molecule inhibitors of lactate dehydrogenase and methods of use thereof

The United States of America, As Represented By The Secretary, Department of Health and Human Services
Fused imidazoles as mIDH1 inhibitors

Bayer Pharma Aktiengesellschaft
Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the same

Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
Tricyclic rho kinase inhibitors

Bristol-Myers Squibb
C5-C6-oxacyclic fused iminothiadiazine dioxide compounds bearing an ether linker as BACE inhibitors, compositions, and their use

Merck Sharp & Dohme
Inhibitors

Probiodrug