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BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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26 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy.EBI
Mitobridge, Inc. (An Astellas)
Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity.EBI
Rapt Therapeutics
The medicinal chemistry of mitochondrial dysfunction: a critical overview of efforts to modulate mitochondrial health.EBI
Msd The Francis Crick Institute
N-(5-SUBSTITUTED-[(1,3,4-THIADIAZOLYL) OR (THIAZOLYL)])(SUBSTITUTED)CARBOXAMIDE COMPOUNDS AND USE THEREOF FOR INHIBITING HUMAN POLYMERASE THETABDB
Repare Therapeutics
MALT1 MODULATORS AND USES THEREOFBDB
Rheos Medicines
2-AMINOPYRIMIDINE COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF AND APPLICATION THEREOFBDB
Guangzhou Salustier Biosciences
CRYSTALLINE FORM OF TLR8 AGONISTBDB
Chia Tai Tianqing Pharmaceutical Group
COMPOUND USEFUL AS CDK7 KINASE INHIBITOR AND USE THEREOFBDB
Tyk Medicines
Treatment of upper aerodigestive tract disorders and coughBDB
Individual
Serine/threonine kinase inhibitorsBDB
Genentech
CompoundsBDB
Tmem16A
Benzamide compoundsBDB
Recurium Ip Holding
Ghrelin O-acyltransferase inhibitorsBDB
Glaxosmithkline Intellectual Property Development
Pyrazolo-heteroaryl derivative, preparation method and medical use thereofBDB
Jiangsu Hengrui Medicine
Substituted imidazo[1,2-c]pyrimidines as PRC2 inhibitorsBDB
Mirati Therapeutics
Oxopicolinamide derivative, preparation method therefor and pharmaceutical use thereofBDB
Jiangsu Hengrui Medicine
Quinolinone lysyl oxidase-like 2 inhibitors and uses thereofBDB
Pharmakea
Aromatic acetylene or aromatic ethylene compound, intermediate, preparation method, pharmaceutical composition and use thereofBDB
TBA
Ethynyl derivativesBDB
Hoffmann-La Roche
Alkyl pyrrolopyrimidine analogs and methods of making and using sameBDB
The University of North Carolina At Chapel Hill
Small molecule inhibitors of lactate dehydrogenase and methods of use thereofBDB
The United States of America, As Represented By The Secretary, Department of Health and Human Services
Fused imidazoles as mIDH1 inhibitorsBDB
Bayer Pharma Aktiengesellschaft
Xanthine derivatives, their use as a medicament, and pharmaceutical preparations comprising the sameBDB
Max-DelbrÜCk-Centrum FÜR Molekulare Medizin
Tricyclic rho kinase inhibitorsBDB
Bristol-Myers Squibb
C5-C6-oxacyclic fused iminothiadiazine dioxide compounds bearing an ether linker as BACE inhibitors, compositions, and their useBDB
Merck Sharp & Dohme
InhibitorsBDB
Probiodrug