50 articles for thisTarget
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X-ray structural and biological evaluation of a series of potent and highly selective inhibitors of human coronavirus papain-like proteases.

Purdue University
Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases.

Korea Research Institute of Bioscience and Biotechnology
Design, synthesis, and evaluation of inhibitors for severe acute respiratory syndrome 3C-like protease based on phthalhydrazide ketones or heteroaromatic esters.

University of Alberta
Bench-to-bedside: Innovation of small molecule anti-SARS-CoV-2 drugs in China.

Qufu Normal University
Novel dithiocarbamates selectively inhibit 3CL protease of SARS-CoV-2 and other coronaviruses.

Univ. Lille
Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery-Genetics Alliance Perspective.

University of Siena
Isatin compounds as noncovalent SARS coronavirus 3C-like protease inhibitors.

Peking University
Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors.

Purdue University
Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors.

Development Center For Biotechnology
Two Binding Sites of SARS-CoV-2 Macrodomain 3 Probed by Oxaprozin and Meclomen.

University of Science and Technology of China
THERAPEUTIC ALKALOID COMPOUNDS

Sensorium Therapeutics
Dihydropyrazolopyrazinone derivative having MGAT2 inhibitory activity

Shionogi
7-phenoxy-N-(3-azabicyclo[3.2.1]octan-8-yl-6,7-dihydro-5H-pyrrolo[1,2-b][1,2,4]triazol-2-amine derivatives and related compounds as gamma- secretase modulators for the treatment of alzheimer's disease

Hoffmann-La Roche
Compounds having PDE9A inhibitory activity, and pharmaceutical uses thereof

Korea Research Institute of Chemical Technology
HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF CANCER

Artios Pharma
SALT TYPES OF TRICYCLIC TETRAHYDRO ISOQUINOLINE DERIVATIVE

Jiangsu Hengrui Pharmaceuticals
Substituted pyrazolo[1,5-a]pyridine compound, composition containing the same and use thereof

Shenzhen Targetrx
KRAS G12D INHIBITOR AND USE THEREOF

Shanghai De Novo Pharmatech
3-[(1H-PYRAZOL-R-YL)OXY]PYRAZIN-2-AMINE COMPOUNDS AS HPK1 INHIBITOR AND USE THEREOF

Beigene
METHODS OF TREATING ACUTE RESPIRATORY DISTRESS SYNDROME WITH ACTIVATORS OF TIE-2

Aerpio Pharmaceuticals
Pyridine and pyrazine compounds as inhibitors of cannabinoid receptor 2

Hoffmann-La Roche
3-AMINO PIPERIDYL SODIUM CHANNEL INHIBITORS

Genentech
SULFONE- AND SULFOXIMINE-BASED SELECTIVE PARP1 INHIBITORS

Enliven
BENZOTHIAZOLE AND QUINOLINE DERIVATIVES FOR USE IN TREATING KAWASAKI DISEASE

Shanghai Yao Yuan Biotechnology Co.
GALACTOPYRANOSYL-CYCLOHEXYL DERIVATIVES AS E-SELECTIN ANTAGONISTS

Glycomimetics
Substituted cyclopenta[c]pyrroles as ABHD6 antagonists

Ono Pharmaceutical Co.
INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE

Cornell University
PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS

Actelion Pharmaceuticals
Diacylglyercol kinase modulating compounds

Gilead Sciences
HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF

Lg Chem
SUBSTITUTED BENZO[f][l ,2,4JTRIAZOL0[4,3-a][l ,4JDIAZEPINES AS GABA A GAMMA! POSITIVE ALLOSTERIC MODULATORS

Hoffmann-La Roche
N-(2-(3-CYANO-2-AZABICYCLO[3.1.0]HEXAN-2-YL)-2-OXOETHYL)QUINOLINE-4-CARBOXAMIDES

Astrazeneca
PYRAZOLEAMIDE DERIVATIVES

Hoffmann-La Roche
Therapeutic compounds and methods of use

Genentech
Compound having PD-L1 inhibitory activity, preparation method therefor and use thereof

Shanghai Ennovabio Pharmaceuticals
Pyrazolopyrimidine compounds as adenosine receptor antagonists

Exscientia
CDK6/DYRK2 DUAL-TARGET INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF

Jiangsu Tasly Diyi Pharmaceutical
Inhibitors of receptor interacting protein kinase I for the treatment of disease

University Of Texas
Compounds and methods for the enhanced degradation of targeted proteins

Arvinas Operations
Azaspirocycles as monoacylglycerol lipase modulators

Janssen Pharmaceutica
KRAS mutant protein inhibitors

Jacobio Pharmaceuticals
Quaternary lactam compound and pharmaceutical use thereof

Shanghai Meiyue Biotech Development
4H-pyrrolo[3,2-c]pyridin-4-one derivatives

Bayer Aktiengesellschaft
Thiazolidinone compounds and use thereof

National Health Research Institute
Small molecule inhibitors of the nuclear translocation of androgen receptor for the treatment of castration-resistant prostate cancer

University of Pittsburgh
2,4-disubstituted pyrimidines as CDK inhibitors

Shanghai Xunhe Pharmaceutical Technology
Inhibitors of pyruvate kinase and methods of treating disease

Beth Israel Deaconess Medical Center
Structure-based design and synthesis of substituted 2-butanols as nonpeptidic inhibitors of HIV protease: secondary amide series.

Agouron Pharmaceuticals