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BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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10 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Development of potent and selective degraders of PI5P4Kγ.EBI
Stanford University
Identification of ARUK2002821 as an isoform-selective PI5P4Kα inhibitor.EBI
University of Cambridge
Discovery and Characterization of the Potent and Highly Selective 1,7-Naphthyridine-Based Inhibitors BAY-091 and BAY-297 of the Kinase PIP4K2A.EBI
Bayer
Development of Selective Phosphatidylinositol 5-Phosphate 4-Kinase γ Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode.EBI
University of Cambridge
Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease.EBI
Glaxosmithkline R&D
Discovery and Structure-Activity Relationship Study of (EBI
Dana-Farber Cancer Institute
Structure-Activity Relationship Study of Covalent Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors.EBI
Dana-Farber Cancer Institute
Discovery of a novel aminopyrazine series as selective PI3Kα inhibitors.EBI
Astrazeneca
Discovery of a series of 8-(1-phenylpyrrolidin-2-yl)-6-carboxamide-2-morpholino-4H-chromen-4-one as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours.EBI
Astrazeneca
TLR8 agonistBDB
Chia Tai Tianqing Pharmaceutical Group