24 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

University of Oxford
Dual-target kinase drug design: Current strategies and future directions in cancer therapy.

Sichuan University
Discovery of a series of 8-(1-phenylpyrrolidin-2-yl)-6-carboxamide-2-morpholino-4H-chromen-4-one as PI3Kβ/δ inhibitors for the treatment of PTEN-deficient tumours.

Astrazeneca
Bicyclic urea kinase inhibitors and uses thereof

The General Hospital
Compositions and methods for treating KIT- and PDGFRA-mediated diseases

Blueprint Medicines
Substituted (4'-hydroxyphenyl)cyclohexane compounds and uses thereof as selective agonists of the estrogen receptor beta isoform

Marquette University
Bipyrazole derivatives as JAK inhibitors

Incyte
Quinazoline derivative and preparation method therefor

Chia Tai Tianqing Pharmaceutical Group
Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitors

Acetylon Pharmaceuticals
Beta-alanine derivatives, pharmaceutically acceptable salts thereof, and pharmaceutical composition comprising same as active ingredient

Korea Research Institute of Chemical Technology
Acid addition salt of substituted pyridine compound

Daiichi Sankyo
Synthetic Triterpenoid Inhibition of Human Ghrelin O-Acyltransferase: The Involvement of a Functionally Required Cysteine Provides Mechanistic Insight into Ghrelin Acylation.

Syracuse University
Chemotype-selective modes of action of ¿-opioid receptor agonists.

University of North Carolina
Potent poxvirus inhibitor

University of Pennsylvania
Substituted amide compounds

Pfizer
Tricyclic indole derivatives useful endothelial lipase inhibitors

Janssen Pharmaceutica
Nitrogen-containing compounds and pharmaceutical compositions thereof for the treatment of atrial fibrillation

Otsuka Pharmaceutical
Treatment of respiratory disorders using TRPA1 antagonists

Glenmark Pharmaceuticals
Design, synthesis and antitumor activity of novel pyrazolo[3,4-d]pyrimidine derivatives as EGFR-TK inhibitors.

Beni-Suef University
ß-Hydroxyacyl-acyl Carrier Protein Dehydratase (FabZ) from Francisella tularensis and Yersinia pestis: Structure Determination, Enzymatic Characterization, and Cross-Inhibition Studies.

Brookhaven National Laboratory
Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein.

Monash University
Benzodioxole piperidine compounds

Hoffmann-La Roche
Tyrosinase inhibition: conformational analysis based studies on molecular dynamics calculations of bipiperidine based inhibitors.

University of Karachi