BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

17 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Recent Progress in Histone Demethylase Inhibitors.EBI
University of Oxford
Inhibition of Histone Demethylases Offers a Novel and Promising Approach for the Treatment of Cancer and Other Diseases.EBI
Therachem Research Medilab (India)
Drug discovery of histone lysine demethylases (KDMs) inhibitors (progress from 2018 to present).EBI
Hangzhou Normal University
Small-Molecule Inhibitors of the MLL1 CXXC Domain, an Epigenetic Reader of DNA Methylation.EBI
University of Virginia
Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors.EBI
Genentech
Identification of potent, selective KDM5 inhibitors.EBI
Constellation Pharmaceuticals
Structure-based design and discovery of potent and selective KDM5 inhibitors.EBI
Celgene
Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.EBI
Celgene Quanticel Research
From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors.EBI
Genentech
Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors.EBI
Sichuan University
Carbocyclic- and heterocyclic-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compoundsBDB
Pfizer
Inhibitors of c-fms kinaseBDB
Janssen Pharmaceutica
Substituted heteroaryl compounds and methods of useBDB
Calitor Sciences
Steroidal 5a-reductase inhibitors using 4-androstenedione as substrate.BDB
Metropolitan University-Xochimilco
Synthesis, molecular docking studies of hybrid benzimidazole as a-glucosidase inhibitor.BDB
Universiti Teknologi Mara (Uitm)
Small Molecule Inhibitors of 8-Oxoguanine DNA Glycosylase-1 (OGG1).BDB
Oregon Health & Science University