27 articles for thisTarget
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Coumarin sulfonates: New alkaline phosphatase inhibitors; in vitro and in silico studies.
University of Karachi
Synthesis, alkaline phosphatase inhibition studies and molecular docking of novel derivatives of 4-quinolones.
Universit£T Rostock
2-Alkoxy-3-(sulfonylarylaminomethylene)-chroman-4-ones as potent and selective inhibitors of ectonucleotidases.
Forman Christian College (A Chartered University)
Synthesis of benzofuran derivatives as selective inhibitors of tissue-nonspecific alkaline phosphatase: effects on cell toxicity and osteoblast-induced mineralization.
University of Lyon
Diarylsulfonamides and their bioisosteres as dual inhibitors of alkaline phosphatase and carbonic anhydrase: Structure activity relationship and molecular modelling studies.
Forman Christian College (A Chartered University)
Synthesis, crystal structure and biological evaluation of some novel 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles and 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines.
Quaid-I-Azam University
Identification of a selective inhibitor of murine intestinal alkaline phosphatase (ML260) by concurrent ultra-high throughput screening against human and mouse isozymes.
Sanford-Burnham Medical Research Institute
Inhibitors of tissue-nonspecific alkaline phosphatase: design, synthesis, kinetics, biomineralization and cellular tests.
University of Lyon
Identification of novel chromone based sulfonamides as highly potent and selective inhibitors of alkaline phosphatases.
Forman Christian College (A Chartered University)
Triazolothiadiazoles and triazolothiadiazines--biologically attractive scaffolds.
Quaid-I-Azam University
Mercaptophosphonate compounds as broad-spectrum inhibitors of the metallo-beta-lactamases.
University of Li£Ge
Design and synthesis of selective inhibitors of placental alkaline phosphatase.
Human Biomolecular Research Institute
Discovery and validation of a series of aryl sulfonamides as selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP).
Institute For Medical Research
Hybrid compounds from chalcone and 1,2-benzothiazine pharmacophores as selective inhibitors of alkaline phosphatase isozymes.
University of Auckland
2-Substituted 7-trifluoromethyl-thiadiazolopyrimidones as alkaline phosphatase inhibitors. Synthesis, structure activity relationship and molecular docking study.
Universit£T Rostock
Discovery of 5-((5-chloro-2-methoxyphenyl)sulfonamido)nicotinamide (SBI-425), a potent and orally bioavailable tissue-nonspecific alkaline phosphatase (TNAP) inhibitor.
Sanford Burnham Prebys Medical Discovery Institute
Developing hybrid molecule therapeutics for diverse enzyme inhibitory action: Active role of coumarin-based structural leads in drug discovery.
Abbottabad University of Science and Technology
Synthesis of sulfadiazinyl acyl/aryl thiourea derivatives as calf intestinal alkaline phosphatase inhibitors, pharmacokinetic properties, lead optimization, Lineweaver-Burk plot evaluation and binding analysis.
Quaid-I-Azam University
Bicyclic heterocyclic derivatives as MNK1 and MNK2 modulators and uses thereof
Agency For Science, Technology and Research
Derivatives of 2-aminopyridine as adenosine A2B receptor antagonists and ligands of the melatonin MT3 receptors
Palobiofarma
Meta-substituted phenyl sulfonyl amides of secondary amino acid amides, the production thereof, and use thereof as matriptase inhibitors
The Medicines Company (Leipzig)
Identification and Characterization of a New Chemotype of Noncovalent SENP Inhibitors.
Beckman Research Institute of The City of Hope
Thiahomoisocitrate: a highly potent inhibitor of homoisocitrate dehydrogenase involved in the alpha-aminoadipate pathway.
Tokyo Institute of Technology
Structure-based de novo design of non-nucleoside adenosine deaminase inhibitors.
Fujisawa Pharmaceutical
4,5-dihydroxypyrimidine carboxamides and N-alkyl-5-hydroxypyrimidinone carboxamides are potent, selective HIV integrase inhibitors with good pharmacokinetic profiles in preclinical species.
Irbm-Mrl