48 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Synthetic 1,2,3-triazole-linked glycoconjugates bind with high affinity to human galectin-3.
Fcfrp - Usp
Synthesis and evaluation of iminocoumaryl and coumaryl derivatized glycosides as galectin antagonists.
Lund University
Tuning the preference of thiodigalactoside- and lactosamine-based ligands to galectin-3 over galectin-1.
Utrecht University
1H-1,2,3-triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors.
The Hashemite University
Galectin-inhibitory thiodigalactoside ester derivatives have antimigratory effects in cultured lung and prostate cancer cells.
Lund University
Synthesis of stable and selective inhibitors of human galectins-1 and -3.
University of Montreal
3-(1,2,3-Triazol-1-yl)-1-thio-galactosides as small, efficient, and hydrolytically stable inhibitors of galectin-3.
Lund University
Synthesis and galectin-binding activities of mercaptododecyl glycosides containing a terminalß-galactosyl group.
National Institute of Advanced Industrial Science and Technology (Aist)
Protein subtype-targeting through ligand epimerization: talose-selectivity of galectin-4 and galectin-8.
Lund University
Ligand Sulfur Oxidation State Progressively Alters Galectin-3-Ligand Complex Conformations To Induce Affinity-Influencing Hydrogen Bonds.
Lund University
Synthesis, binding affinity, and inhibitory capacity of cyclodextrin-based multivalent glycan ligands for human galectin-3.
University of Maryland
Identification of benzothiazole derived monosaccharides as potent, selective, and orally bioavailable inhibitors of human and mouse galectin-3; a rare example of using a S···O binding interaction for drug design.
Bristol Myers Squibb
Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia.
Griffith University
Identification of Monosaccharide Derivatives as Potent, Selective, and Orally Bioavailable Inhibitors of Human and Mouse Galectin-3.
Bristol Myers Squibb
Discovery and Optimization of the First Highly Effective and Orally Available Galectin-3 Inhibitors for Treatment of Fibrotic Disease.
Galecto Biotech
Synthesis, Structure-Activity Relationships, and In Vivo Evaluation of Novel Tetrahydropyran-Based Thiodisaccharide Mimics as Galectin-3 Inhibitors.
Bristol Myers Squibb
Benzimidazole-galactosides bind selectively to the Galectin-8 N-Terminal domain: Structure-based design and optimisation.
Lund University
Structure-Guided Design of d-Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain.
Lund University
Quinoline-Pyrazole Scaffold as a Novel Ligand of Galectin-3 and Suppressor of TREM2 Signaling.
Stanford University School of Medicine
A Selective Galactose-Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model.
Institute of Science Education and Research-Kolkata (Iiser) Kolkata
Binding of triazole-linked galactosyl arylsulfonamides to galectin-3 affects Trypanosoma cruzi cell invasion.
University of Sao Paulo
Bivalent O-glycoside mimetics with S/disulfide/Se substitutions and aromatic core: Synthesis, molecular modeling and inhibitory activity on biomedically relevant lectins in assays of increasing physiological relevance.
Ludwig-Maximilians-University Munich
Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity.
Lund University
Phenoxyacetic acid derivatives, preparation method thereof and use thereof as medicament
China Pharmaceutical University
Pharmaceutical composition for preventing or treating acute myeloid leukemia or metastatic breast cancer
Pelemed
2-oxoquinazoline derivatives as methionine adenosyltransferase 2A inhibitors
Ideaya Biosciences
2-aryl-4-hydroxy-1,3-thiazole derivatives useful as TRPM8-inhibitors in treatment of neuralgia, pain, COPD and asthma
DompÉ
Substituted pyrrolopyridine JAK inhibitors and methods of making and using the same
Aclaris Therapeutics
Tetrahydrothiophene-based GABA aminotransferase inactivators and analogs thereof for treating neurological disorders
Northwestern University
Haloallylamine indole and azaindole derivative inhibitors of lysyl oxidases and uses thereof
Pharmaxis