The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 708K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

23 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Recent advances in the discovery and development of antibacterial agents targeting the cell-division protein FtsZ.EBI
Stony Brook University
Synthesis and Evaluation of Quinazolines as Inhibitors of the Bacterial Cell Division Protein FtsZ.EBI
University of California Davis
Design, synthesis and antibacterial activity of cinnamaldehyde derivatives as inhibitors of the bacterial cell division protein FtsZ.EBI
Shandong University
Advances in the discovery of novel antimicrobials targeting the assembly of bacterial cell division protein FtsZ.EBI
Shandong University
Chrysophaentins are competitive inhibitors of FtsZ and inhibit Z-ring formation in live bacteria.EBI
National Institute of Diabetes and Digestive and Kidney Diseases
3-Phenyl substituted 6,7-dimethoxyisoquinoline derivatives as FtsZ-targeting antibacterial agents.EBI
The State University of New Jersey
A bactericidal guanidinomethyl biaryl that alters the dynamics of bacterial FtsZ polymerization.EBI
University of Medicine and Dentistry of New Jersey
The Synthesis and Antimicrobial Activity of Heterocyclic Derivatives of Totarol.EBI
TBA
Novel trisubstituted benzimidazoles, targeting Mtb FtsZ, as a new class of antitubercular agents.EBI
State University of New York
Parallel solid synthesis of inhibitors of the essential cell division FtsZ enzyme as a new potential class of antibacterials.EBI
Laval University
Novel pyridopyrazine and pyrimidothiazine derivatives as FtsZ inhibitors.EBI
Southern Research Institute
Probing the binding site of curcumin in Escherichia coli and Bacillus subtilis FtsZ--a structural insight to unveil antibacterial activity of curcumin.EBI
National Institute of Pharmaceutical Education and Research
Bacterial GTPases as druggable targets to tackle antimicrobial resistance.EBI
Indian Institute of Science Education and Research Bhopal
The cell division protein FtsZ as a cellular target to hit cystic fibrosis pathogens.EBI
University of Pavia
The natural anthraquinone dye purpurin exerts antibacterial activity by perturbing the FtsZ assembly.EBI
National Institute of Technology Calicut
Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study.EBI
Guangdong University of Technology
Discovery of FtsZ inhibitors by virtual screening as antibacterial agents and study of the inhibition mechanism.EBI
The Hong Kong Polytechnic University
Targeting the FtsZ Allosteric Binding Site with a Novel Fluorescence Polarization Screen, Cytological and Structural Approaches for Antibacterial Discovery.EBI
Csic
Design, synthesis and evaluation of novel 9-arylalkyl-10-methylacridinium derivatives as highly potent FtsZ-targeting antibacterial agents.EBI
Shandong University
Targeting the Bacterial Division Protein FtsZ.EBI
University of Wisconsin-Madison
An inhibitor of FtsZ with potent and selective anti-staphylococcal activity.EBI
Prolysis
[125I]A-312110, a novel high-affinity 1,4-dihydropyridine ATP-sensitive K+ channel opener: characterization and pharmacology of binding.BDB
Abbott Laboratories
A series of potent and selective, triazolylphenyl-based histone deacetylases inhibitors with activity against pancreatic cancer cells and Plasmodium falciparum.BDB
University of Illinois At Chicago