BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

8 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of Second Generation Reversible Covalent DPP1 Inhibitors Leading to an Oxazepane Amidoacetonitrile Based Clinical Candidate (AZD7986).EBI
Charles River Discovery Research Services
Grassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation.EBI
University of Florida
The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K.EBI
Merck Frosst Centre For Therapeutic Research
Identification and optimization of inhibitors of Trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB.EBI
National Human Genome Research Institute
Structure-activity relationships of triazole-benzodioxine inhibitors of cathepsin X.EBI
University of Ljubljana
Pyranopyrazole and pyrazolopyridine immunomodulators for treatment of autoimmune diseasesBDB
Rockefeller University
Substituted carbonucleoside derivatives useful as anticancer agentsBDB
Pfizer
Tetrahydroisoquinolines containing substituted azoles as factor XIa inhibitorsBDB
Bristol-Myers Squibb