The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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5 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Inhibitors of LRRK2 kinaseBDB
Halia Therapeutics
Compounds inhibiting leucine-rich repeat kinase enzyme activityBDB
Merck Sharp & Dohme
The Parkinson disease-linked LRRK2 protein mutation I2020T stabilizes an active state conformation leading to increased kinase activity.BDB
Harvard Neurodiscovery Center
Aminopyridine derived compounds as LRRK2 inhibitorsBDB
H. Lundbeck
Arylpyrrolopyridine derived compounds as LRRK2 inhibitorsBDB
H. Lundbeck