BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.5M data for 728K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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18 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of a novel small molecule agonist scaffold for the APJ receptor.EBI
Rti International
Pyrazole antagonists of the CB1 receptor with reduced brain penetration.EBI
Rti International
The amide linker in nonpeptide neurotensin receptor ligands plays a key role in calcium signaling at the neurotensin receptor type 2.EBI
Rti International
Hybrid dopamine uptake blocker-serotonin releaser ligands: a new twist on transporter-focused therapeutics.EBI
Rti International
Identifying structural determinants of potency for analogs of apelin-13: integration of C-terminal truncation with structure-activity.EBI
Rti International
Synthesis and pharmacology of 1-alkyl-3-(1-naphthoyl)indoles: steric and electronic effects of 4- and 8-halogenated naphthoyl substituents.EBI
Rti International
Synthesis and identification of novel 11beta-aryl-4',5'-dihydrospiro[estra-4,9-diene-17beta,4'-oxazole] analogs with dissociated antiprogesterone activities.EBI
Rti International
Towards rational design of cannabinoid receptor 1 (CB1) antagonists for peripheral selectivity.EBI
Rti International
Amiodarone and its putative metabolites fail to activate wild type hTAAR1.EBI
Rti International
Structure-activity correlations for beta-phenethylamines at human trace amine receptor 1.EBI
Rti International
Neuropeptide B/W receptor 1 peptidomimetic agonists: Structure-activity relationships and plasma stability.EBI
Rti International
Synthesis and characterization of an orally bioavailable small molecule agonist of the apelin receptor.EBI
Rti International
Pyrazole Agonist of the Apelin Receptor Improves Symptoms of Metabolic Syndrome in Mice.EBI
Rti International
Identification of potent pyrazole based APELIN receptor (APJ) agonists.EBI
Rti International
Functionalized 6-(piperidin-1-yl)-8,9-diphenyl purines as inverse agonists of the CB1 receptor - SAR efforts towards selectivity and peripheralization.EBI
Rti International
Functionalized 6-(Piperidin-1-yl)-8,9-Diphenyl Purines as Peripherally Restricted Inverse Agonists of the CB1 Receptor.EBI
Rti International
Synthesis and pharmacological characterization of functionalized 6-piperazin-1-yl-purines as cannabinoid receptor 1 (CB1) inverse agonists.EBI
Rti International
Blocking Alcoholic Steatosis in Mice with a Peripherally Restricted Purine Antagonist of the Type 1 Cannabinoid Receptor.EBI
Rti International