The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

15 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis of (3,4-dimethoxyphenoxy)alkylamino acetamides as orexin-2 receptor antagonists.EBI
Pharmacopeia
Identification of potent inhibitors of Plasmodium falciparum plasmepsin II from an encoded statine combinatorial library.EBI
Pharmacopeia
Novel pyrrolidine ureas as C-C chemokine receptor 1 (CCR1) antagonists.EBI
Pharmacopeia
Synthesis and SAR studies of trisubstituted purinones as potent and selective adenosine A2A receptor antagonists.EBI
Pharmacopeia
Synthesis and initial evaluation of novel, non-peptidic antagonists of the alpha(v)-integrins alpha(v)beta(3) and alpha(v)beta(5).EBI
Pharmacopeia
Synthesis of 2-amino-5-benzoyl-4-(2-furyl)thiazoles as adenosine A(2A) receptor antagonists.EBI
Pharmacopeia
Sulfonamido-aryl ethers as bradykinin B1 receptor antagonists.EBI
Pharmacopeia
Synthesis and structure-activity relationships of new disubstituted phenyl-containing 3,4-diamino-3-cyclobutene-1,2-diones as CXCR2 receptor antagonists.EBI
Pharmacopeia
Guiding farnesyltransferase inhibitors from an ECLiPS library to the catalytic zinc.EBI
Pharmacopeia
Fast small molecule similarity searching with multiple alignment profiles of molecules represented in one-dimension.EBI
Pharmacopeia
Surfing the piperazine core of tricyclic farnesyltransferase inhibitors.EBI
Pharmacopeia
Small molecule biaryl FSH receptor agonists. Part 2: Lead optimization via parallel synthesis.EBI
Pharmacopeia
Small molecule biaryl FSH receptor agonists. Part 1: Lead discovery via encoded combinatorial synthesis.EBI
Pharmacopeia
2-(Aminomethyl)-benzamide-based glycine transporter type-2 inhibitors.EBI
Pharmacopeia
Evaluation of a structure-based statine cyclic diamino amide encoded combinatorial library against plasmepsin II and cathepsin D.EBI
Pharmacopeia