The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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17 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Sebetralstat (KVD900): A Potent and Selective Small Molecule Plasma Kallikrein Inhibitor Featuring a Novel P1 Group as a Potential Oral On-Demand Treatment for Hereditary Angioedema.EBI
Kalvista Pharmaceuticals
4-AMINO-3-(4-PHENOXYPHENYL)-1,3-DIHYDRO-2H-IMIDAZO[4,5-C]PYRIDIN-2-ONE DERIVATIVES AND SALTS THEREOFBDB
Genzyme
Cyclic dinucleotides as sting agonistsBDB
Janssen Biotech
BRD4 inhibitorBDB
Hinova Pharmaceuticals
Purine inhibitors of human phosphatidylinositol 3-kinase deltaBDB
Merck Sharp & Dohme
Pyrazole derivatives as plasma kallikrein inhibitorsBDB
Kalvista Pharmaceuticals
Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulatorBDB
Vertex Pharmaceuticals
Monocyclic thieno, pyrido, and pyrrolo pyrimidine compounds and methods of use and manufacture of sameBDB
Duquesne University of The Holy Spirit
Pyrrolidine derivativeBDB
Kissei Pharmaceutical
ULK1 inhibitors and methods using sameBDB
Salk Institute For Biological Studies
Bruton's tyrosine kinase inhibitorsBDB
Zibo Biopolar Changsheng Pharmaceutical
Deciphering the binding of caveolin-1 to client protein endothelial nitric-oxide synthase (eNOS): scaffolding subdomain identification, interaction modeling, and biological significance.BDB
St. Paul'S Hospital'S Centre of Heart and Lung Innovation
Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability.BDB
National Institutes of Health, National Institutes of Health Biomedical Research Center
Phenylimidazole derivatives as PDE10A enzyme inhibitorsBDB
H. Lundbeck
Pyrimidinecarboxamides as CXCR2 modulatorsBDB
Syntrix Biosystems
Heterocyclic substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compoundsBDB
Pfizer
Synthesis and Biological Evaluation of 3-thiazolocoumarinyl Schiff-base Derivatives as Cholinesterase Inhibitors.BDB
Comsats Institute of Information Technology