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BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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13 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)-¿ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate.EBI
Infinity Pharmaceuticals
Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors.EBI
Infinity Pharmaceuticals
Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90.EBI
Infinity Pharmaceuticals
Discovery of a potent and orally active hedgehog pathway antagonist (IPI-926).EBI
Infinity Pharmaceuticals
Diversity-oriented synthesis of a cytisine-inspired pyridone library leading to the discovery of novel inhibitors of Bcl-2.EBI
Infinity Pharmaceuticals
DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 MBDB
Baylor College of Medicine
Azetidine derivativesBDB
Vernalis (R&D)
Rho kinase inhibitorsBDB
Kadmon
Cycloalkane derivativesBDB
Daiichi Sankyo
Substituted 4-phenylpiperidines, their preparation and useBDB
Columbia University
Methylene linked quinolinyl modulators of RORγtBDB
Janssen Pharmaceutica
Chemotype-selective modes of action of ¿-opioid receptor agonists.BDB
University of North Carolina