The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

23 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Implications of promiscuous Pim-1 kinase fragment inhibitor hydrophobic interactions for fragment-based drug design.EBI
Genzyme
Design and synthesis of pyridin-2-ylmethylaminopiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic (R5) HIV-1 replication.EBI
Genzyme
The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors.EBI
Genzyme
Design and synthesis of pyridin-2-yloxymethylpiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic (R5) HIV-1 replication.EBI
Genzyme
Design of novel CXCR4 antagonists that are potent inhibitors of T-tropic (X4) HIV-1 replication.EBI
Genzyme
Novel S-adenosylmethionine decarboxylase inhibitors for the treatment of human African trypanosomiasis.EBI
Genzyme
Synthesis and SAR of novel CXCR4 antagonists that are potent inhibitors of T tropic (X4) HIV-1 replication.EBI
Genzyme
Discovery of novel sphingosine kinase-1 inhibitors. Part 2.EBI
Genzyme
Discovery of novel small molecule orally bioavailable C-X-C chemokine receptor 4 antagonists that are potent inhibitors of T-tropic (X4) HIV-1 replication.EBI
Genzyme
Discovery of novel sphingosine kinase 1 inhibitors.EBI
Genzyme
Discovery of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid diamides that increase CFTR mediated chloride transport.EBI
Genzyme
CAMPTOTHECIN DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOFBDB
Simcere Zaiming Pharmaceutical Co.
Imidazopyridinone compoundBDB
Kissei Pharmaceutical
NOVEL BIPHENYL DERIVATIVE AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOFBDB
Xi'An Xinton Pharmaceutcal Research
SUBSTITUTED 1H-PYRROLO[3,2-B]PYRIDINE COMPOUNDS AND METHODS OF USE THEREOFBDB
Bayer Aktiengesellschaft
JAK kinase inhibitor and preparation method and use thereofBDB
Shanghai Longwood Biopharmaceuticals
Amino acid compounds with unbranched linkers and methods of useBDB
Pliant Therapeutics
Maslinic and oleanolic acids derivatives for treating SARS-CoV-2 infectionBDB
King Abdulaziz University
Methods of treating mental disordersBDB
University of California
(5s,8s)-3-(4′-chlor-3′-fluor-4-methlybiphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5] dec-3-en-2-one (compound A) for treatmentBDB
Bayer Intellectual Property
Protease inhibitorsBDB
Medivir
Differential agonist inhibition identifies multiple epibatidine binding sites in mouse brain.BDB
University of Colorado