BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

36 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Synthesis and biological evaluation of novel cyclosporin a analogues: potential soft drugs for the treatment of autoimmune diseases.EBI
Enanta Pharmaceuticals
TAU-TUBULIN KINASE (TTBK) INHIBITOR COMPOUNDSBDB
Csic
COMPOUND CONTAINING CYCLOALKYL OR HALOALKYLBDB
Chia Tai Tianqing Pharmaceutical Group Co.
SALT TYPES OF TRICYCLIC TETRAHYDRO ISOQUINOLINE DERIVATIVEBDB
Jiangsu Hengrui Pharmaceuticals
GALACTOPYRANOSYL-CYCLOHEXYL DERIVATIVES AS E-SELECTIN ANTAGONISTSBDB
Glycomimetics
PIPERIDINYLPYRIDINYLCARBONITRILE DERIVATIVES AS INHIBITORS OF GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE AND GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE PROTEINBDB
Boehringer Ingelheim International
N-(2-(3-CYANO-2-AZABICYCLO[3.1.0]HEXAN-2-YL)-2-OXOETHYL)QUINOLINE-4-CARBOXAMIDESBDB
Astrazeneca
USP30 inhibitors and uses thereofBDB
Vincere Biosciences
Pyrazolopyrimidine compounds as adenosine receptor antagonistsBDB
Exscientia
Isoquinolin-3-yl carboxamides and preparation and use thereofBDB
Biosplice Therapeutics
Modulators of methyl modifying enzymes, compositions and uses thereofBDB
Constellation Pharmaceuticals
Heterocyclic compound as JAK inhibitor, and salts and therapeutic use thereofBDB
Suzhou Longbiotech Pharmaceuticals
Galactoside inhibitor of galectinsBDB
Galecto Biotech
KRAS mutant protein inhibitorsBDB
Jacobio Pharmaceuticals
Quaternary lactam compound and pharmaceutical use thereofBDB
Shanghai Meiyue Biotech Development
hTRPV1 chemical agentsBDB
University of Pittsburgh
Optically active crosslinked cyclic secondary amine derivativeBDB
Sumitomo Dainippon Pharma
Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic diseaseBDB
Shy Therapeutics
Compound for inhibiting IDO, a manufacturing method and a use thereofBDB
Shanghai Joyu Pharmatech
Oxazole derivatives for use in the treatment of cancerBDB
Lifearc
Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapyBDB
The Johns Hopkins University
ABHD6 and dual ABHD6/MGL inhibitors and their usesBDB
Makscientific
Benzimidazole derivatives as PI3 kinase inhibitorsBDB
Glaxosmithkline
Certain chemical entities, compositions, and methodsBDB
Neupharma
Amino pyrimidine derivativesBDB
Novartis
Heterocyclic inhibitors of ATR kinaseBDB
University Of Texas
Imidazothiadiazole and imidazopyrazine derivatives as protease activated receptor 4 (PAR4) inhibitors for treating platelet aggregationBDB
Bristol-Myers Squibb
P2X7 modulatorsBDB
Janssen Pharmaceutica
New protein farnesyltransferase inhibitors in the 3-arylthiophene 2-carboxylic acid series: diversification of the aryl moiety by solid-phase synthesis.BDB
Centre De Recherche De Gif
Kinase inhibitorsBDB
Allergan
Aminopyridine derived compounds as LRRK2 inhibitorsBDB
H. Lundbeck
N-[4-(1H-pyrazolo[3,4-b]pyrazin-6-yl)-phenyl]-sulfonamides and their use as pharmaceuticalsBDB
Sanofi
Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a ]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline and use thereofBDB
Bristol-Myers Squibb
A photorhabdus natural product inhibits insect juvenile hormone epoxide hydrolase.BDB
Goethe Universität Frankfurt