39 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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Design, synthesis and biological evaluation of novel 4-phenylisoquinolinone BET bromodomain inhibitors.
Celgene Quanticel Research
Design of KDM4 Inhibitors with Antiproliferative Effects in Cancer Models.
Celgene Quanticel Research
N-(phenylsulfonyl)benzamides and related compounds as Bcl-2 inhibitors
University of Michigan
Substituted isoindolin-1-ones and 2,3-dihydro-1H-pyrrol[3,4-c]pyridin-1-ones as HPK1 antagonists
Nimbus Saturn
Type of aryl benzofuran amidated derivative and medical use thereof
China Pharmaceutical University
Tetrazole containing apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof
Enanta Pharmaceuticals
Rational Design of Hybrid SARS-CoV-2 Main Protease Inhibitors Guided by the Superimposed Cocrystal Structures with the Peptidomimetic Inhibitors GC-376, Telaprevir, and Boceprevir.
The University of Arizona
Nitrogen-containing heterocyclic amide compound and pharmaceutical use thereof
Japan Tobacco
Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors
Forma Therapeutics
Polyfluorinated compounds acting as bruton tyrosine kinase inhibitors
Zhejiang Dtrm Biopharma
Designing modulators of dimethylarginine dimethylaminohydrolase (DDAH): a focus on selectivity over arginase.
Christian-Albrechts-University
Steroidal 5a-reductase inhibitors using 4-androstenedione as substrate.
Metropolitan University-Xochimilco
Rationalizing the Binding Kinetics for the Inhibition of the Burkholderia pseudomallei FabI1 Enoyl-ACP Reductase.
Stony Brook University
Substituted furans as potent lipoxygenase inhibitors: Synthesis, in vitro and molecular docking studies.
Csir-Indian Institute of Chemical Biology
Discovery of imidazopyridine derivatives as novel c-Met kinase inhibitors: Synthesis, SAR study, and biological activity.
China Pharmaceutical University
Reverse Biosynthesis: Generating Combinatorial Pools of Drug Leads from Enzyme-Mediated Fragmentation of Natural Products.
The University of Sydney
Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor.
Genentech
Cyclohexylamine derivatives having β2 adrenergic agonist and M3 muscarinic antagonist activities
Almirall
A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.
Whitehead Institute For Biomedical Research
Design, synthesis and biological evaluation of 1H-pyrrolo[2,3-b]pyridine and 1H-pyrazolo[3,4-b]pyridine derivatives as c-Met inhibitors.
Tianjin University of Science and Technology
Azetidine derivative and antidepressant composition including the same
Korea Institute of Science and Technology
4-(pyridin-3-yl)-2(pyridin-2yl)-1,2-dihydro-3H-pyrazol-3-one derivatives as specific HIF-pyrolyl-4-hydroxylase inhibitors for treating cardiovascular and haematological diseases
Bayer Intellectual Property
Small Molecule Inhibitors of 8-Oxoguanine DNA Glycosylase-1 (OGG1).
Oregon Health & Science University