BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 698K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

29 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery, Development, and SAR of Aminothiazoles as LIMK Inhibitors with Cellular Anti-Invasive Properties.EBI
Cancer Research Technology
NOVEL COMPOUNDS AND THEIR USEBDB
Debiopharm International
OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOFBDB
Eikonizo Therapeutics
Treatment of autism spectrum disorders, obsessive-compulsive disorder and anxiety disordersBDB
Rugen Holdings (Cayman)
Compounds and methods of useBDB
Medivation Technologies
Histone deacetylase inhibitors for immunomodulation in tumor microenvironmentBDB
Great Novel Therapeutics Biotech & Medicals
Pyrazolochlorophenyl compounds, compositions and methods of use thereofBDB
Genentech
Therapeutic compounds and methods of use thereofBDB
Agency For Science, Technology and Research (A*Star)
Aminoimidazopyridazines as kinase inhibitorsBDB
Bristol-Myers Squibb
Benzopyrazole compound used as RHO kinase inhibitorBDB
Medshine Discovery
Compounds that inhibits MCL-1 proteinBDB
Amgen
Substituted thiohydantoin derivatives as androgen receptor antagonistsBDB
Janssen Pharmaceutica
Bis-heteroaryl derivatives as modulators of protein aggregationBDB
Ucb Biopharma
PRMT5 inhibitorsBDB
Merck Sharp & Dohme
Inhibitors of integrin alpha 5 beta 1 and methods of useBDB
University of California
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.BDB
University of North Carolina At Chapel Hill
Screening of drugs by FRET analysis identifies inhibitors of SARS-CoV 3CL protease.BDB
National Taiwan University
Small molecule inhibitors of the JAK family of kinasesBDB
Janssen Pharmaceutica
Tetrahydronaphthalene estrogen receptor modulators and uses thereofBDB
Genentech
NOVEL PHTHALAZINE DERIVATIVE HAVING ECTONUCLOEOTIDE PYROPHOSPHATASE/PHOSPHODIESTE RASE INHIBITORY ACTIVITY, AND USE THEREOFBDB
Txinno Bioscience
Oxamic acid analogues as LDH-C4-specific competitive inhibitors.BDB
Instituto Politécnico Nacional
Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomasBDB
The United States of America, As Represented By The Secretary, Department of Health and Human Services
Small-molecule WNK inhibition regulates cardiovascular and renal function.BDB
Novartis Institutes
Disubstituted benzothienyl-pyrrolotriazines and uses thereofBDB
Bayer Intellectual Property
Phospholipid drug analogsBDB
Telormedix
Compounds and methods for treating bacterial infectionsBDB
Astrazeneca
Quinazoline compounds as kinase inhibitorsBDB
Development Center For Biotechnology
Pyrrolo[2,3-D]pyrimidine compoundsBDB
Pfizer