BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.5M data for 737K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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21 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of BLU-945, a Reversible, Potent, and Wild-Type-Sparing Next-Generation EGFR Mutant Inhibitor for Treatment-Resistant Non-Small-Cell Lung Cancer.EBI
Blueprint Medicines
Inhibition of histone methyl transferases to treat cancerBDB
Albert-Ludwigs-Universitat Freiburg
AROMATIC HETEROCYCLE-SUBSTITUTED COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOFBDB
Innovstone Therapeutics
SELECTIVE HYPOTHALAMUS PERMEABLE HDAC6 INHIBITORS FORTREATMENT OF LEPTIN-RESISTANT OBESITYBDB
The Children’S Medical Center
Substituted piperazines as selective HDAC1,2 inhibitorsBDB
Regenacy Pharmaceuticals
Substituted heteroaromatic pyrazolo-pyridines and their use as GLUN2B receptor modulatorsBDB
Janssen Pharmaceutica
Indazole compound for use in inhibiting kinase activity, composition and application thereofBDB
Shenzhen Targetrx
Hydantoins that modulate BACE-mediated app processingBDB
Buck Institute For Research On Aging
Pyridinyl pyrazoles as modulators of RORγTBDB
Janssen Pharmaceutica
Inhibitors of Bruton's tyrosine kinase and methods of their useBDB
Janssen Pharmaceutica
Substituted pyrrolo[2,3-d]pyridazin-4-ones and pyrazolo[3,4-d]pyridazin-4-ones as protein kinase inhibitorsBDB
Shanghai Fochon Pharmaceutical
Mammalian and bacterial nitric oxide synthase inhibitorsBDB
Northwestern University
Triazolones and tetrazolones as inhibitors of ROCKBDB
Bristol-Myers Squibb
Benzazepine dicarboxamide compounds with tertiary amide functionBDB
Hoffmann-La Roche
Ribonucleotide reductase inhibitors and methods of useBDB
City of Hope
Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activityBDB
Boehringer Ingelheim International
Synthesis of new 8(S)-HETE analogs and their biological evaluation as activators of the PPAR nuclear receptors.BDB
Universit�� De Rennes 1
Synthesis, in vitro ß-glucuronidase inhibitory activity and in silico studies of novel (E)-4-Aryl-2-(2-(pyren-1-ylmethylene)hydrazinyl)thiazoles.BDB
University of Karachi
LSD1 Substrate Binding and Gene Expression Are Affected by HDAC1-Mediated Deacetylation.BDB
Wayne State University
Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapyBDB
Abbvie Deutschland