The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.2M data for 1.4M Compounds and 11.4K Targets. Of those, 1.6M data for 748K Compounds and 4.8K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

10 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Exploration of SAR features by modifications of thiazoleacetic acids as CRTH2 antagonists.EBI
7Tm Pharma
Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 1.EBI
7Tm Pharma
Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2.EBI
7Tm Pharma
Conversion of 4-cyanomethyl-pyrazole-3-carboxamides into CB1 antagonists with lowered propensity to pass the blood-brain-barrier.EBI
7Tm Pharma
Exploring SAR features in diverse library of 4-cyanomethyl-pyrazole-3-carboxamides suitable for further elaborations as CB1 antagonists.EBI
7Tm Pharma
Novel selective orally active CRTH2 antagonists for allergic inflammation developed from in silico derived hits.EBI
7Tm Pharma
6-Acylamino-2-amino-4-methylquinolines as potent melanin-concentrating hormone 1 receptor antagonists: structure-activity exploration of eastern and western parts.EBI
7Tm Pharma
6-Acylamino-2-aminoquinolines as potent melanin-concentrating hormone 1 receptor antagonists. Identification, structure-activity relationship, and investigation of binding mode.EBI
7Tm Pharma
Minor structural modifications convert the dual TP/CRTH2 antagonist ramatroban into a highly selective and potent CRTH2 antagonist.EBI
7Tm Pharma
4-Acylamino-and 4-ureidobenzamides as melanin-concentrating hormone (MCH) receptor 1 antagonists.EBI
7Tm Pharma