BindingDB Data by Journal
PMID
Data
Article Title
Citation
Organization
Download Data
Evidence for substrate-dependent inhibition profiles for human liver aldehyde oxidase.
Drug Metab Dispos 41: 24-9 (2012)
Washington State University
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Drug Metab Dispos 41: 60-71 (2012)
Tongji University
Evaluation and prediction of potential drug-drug interactions of linagliptin using in vitro cell culture methods.
Drug Metab Dispos 41: 149-58 (2012)
Nippon Boehringer Ingelheim
Clinical pharmacokinetics, metabolism, and drug-drug interaction of carfilzomib.
Drug Metab Dispos 41: 230-7 (2012)
Onyx Pharmaceuticals
Quantitative prediction of CYP2B6 induction by estradiol during pregnancy: potential explanation for increased methadone clearance during pregnancy.
Drug Metab Dispos 41: 270-4 (2013)
Amgen
In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor.
Drug Metab Dispos 41: 353-61 (2013)
Glaxosmithkline
Regiospecificity and stereospecificity of human UDP-glucuronosyltransferases in the glucuronidation of estriol, 16-epiestriol, 17-epiestriol, and 13-epiestradiol.
Drug Metab Dispos 41: 582-91 (2013)
University of Helsinki
Amide hydrolysis of a novel chemical series of microsomal prostaglandin E synthase-1 inhibitors induces kidney toxicity in the rat.
Drug Metab Dispos 41: 634-41 (2013)
Astrazeneca
Reversible inhibition of human carboxylesterases by acyl glucuronides.
Drug Metab Dispos 41: 698-703 (2013)
Eisai
Pharmacokinetics, metabolism, and excretion of the glycogen synthase kinase-3 inhibitor LY2090314 in rats, dogs, and humans: a case study in rapid clearance by extensive metabolism with low circulating metabolite exposure.
Drug Metab Dispos 41: 714-26 (2013)
Eli Lilly
Organic anion transporter 3 interacts selectively with lipophilicß-lactam antibiotics.
Drug Metab Dispos 41: 791-800 (2013)
Wilkes University
Metabolites of PPI-2458, a selective, irreversible inhibitor of methionine aminopeptidase-2: structure determination and in vivo activity.
Drug Metab Dispos 41: 814-26 (2013)
Glaxosmithkline
The inactivation of human CYP2E1 by phenethyl isothiocyanate, a naturally occurring chemopreventive agent, and its oxidative bioactivation.
Drug Metab Dispos 41: 858-69 (2013)
University of Michigan Medical School
Potential role of UGT1A4 promoter SNPs in anastrozole pharmacogenomics.
Drug Metab Dispos 41: 870-7 (2013)
University of Arkansas For Medical Sciences
Absorption, elimination, and metabolism of CS-1036, a novela-amylase inhibitor in rats and monkeys, and the relationship between gastrointestinal distribution and suppression of glucose absorption.
Drug Metab Dispos 41: 878-87 (2013)
Daiichi Sankyo
Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1.
Drug Metab Dispos 41: 916-22 (2013)
Gilead Sciences
Interaction of silymarin flavonolignans with organic anion-transporting polypeptides.
Drug Metab Dispos 41: 958-65 (2013)
University of North Carolina At Chapel Hill